1. 重组蛋白
  2. Cytokines and Growth Factors

Cytokines and Growth Factors  (细胞因子和生长因子)

细胞因子是一类由多种免疫细胞(如巨噬细胞、淋巴细胞和肥大细胞等)以及某些非免疫细胞(如内皮细胞、表皮细胞等)分泌的低分子量可溶性蛋白/多肽/糖蛋白。细胞因子在调节细胞生长、分化和激活中发挥重要作用,并参与先天和适应性免疫反应。细胞因子包括:白介素、趋化因子、干扰素等[1][2][3]。生长因子是一类可溶性信号分子,能够在发育和组织愈合过程中刺激细胞增殖、迁移、分化和多细胞形态发生。生长因子通常为分泌蛋白或甾体激素[4][5]。专业术语 “生长因子”和“细胞因子”常通用。某些多肽生长因子为细胞因子。影响细胞生长分化信号途径的细胞因子被认为是生长因子,如 GM-CSF[5][6]

Cytokines are a large group of low molecular weight proteins, polypeptides or glycoproteins that are secreted by various immune cells including macrophages, lymphocytes and mast cells, as well as other cell types such as endothelial cells. They play important roles in regulating cell growth, differentiation, and activation, and are involved in many aspects of both innate and adaptive immune responses. Cytokines include interleukins, chemokines, interferons and other signalling molecules[1][2][3].
Growth factors are soluble signaling molecules capable of stimulating a variety of cellular processes including cell proliferation, migration, differentiation and multicellular morphogenesis during development and tissue healing. Usually, Growth factors are secreted proteins or steroid hormones[4][5].
The term “Growth factor” and “Cytokine” are often used interchangeably. Some growth factors are small peptides called cytokines. The cytokines affecting cell growth/differentiation signaling pathways are considered growth factors, such as GM-CSF[5][6].

目录号 产品名 / 同用名 种属 表达系统
  • HY-P7018
    IGF-I/IGF-1 Protein, Human (70a.a)

    重组人胰岛素样生长因子-1

    rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I

    Human E. coli
    IGF-I/IGF-1 Protein, Human (70a.a)是一种促进有丝分裂的细胞因子,与 IGF 受体结合,能够调节多种组织的生长,如神经组织、淋巴组织、生殖组织、平滑肌、内皮细胞和骨骼等,同时具有调节神经保护的作用。
  • HY-P7077
    IL-2 Protein, Mouse

    rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Mouse E. coli
    IL-2 Protein, Mouse是一种免疫调节细胞因子,具有广泛的功能,包括促进细胞凋亡,增殖和淋巴细胞的存活。
  • HY-P7118
    TGF beta 1/TGFB1 Protein, Human

    重组人 TGF beta 1/TGFB1 蛋白

    TGF-beta-1; TGFB1; TGFB; rHuTGF-β1

    Human CHO
    TGF beta 1/TGFB1 蛋白最初被认为是一种诱导啮齿动物成纤维细胞生长的生长因子。TGF beta 1/TGFB1 蛋白可将细胞阻滞在 G1 期。TGF beta 1/TGFB1 是内源性调节细胞凋亡的因子。重组人 TGF beta 1/TGFB1 蛋白 是由 CHO 细胞表达的,A279-S390 片段的蛋白。
  • HY-P7037
    IL-2 Protein, Human

    rHuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Human E. coli
    IL-2 Protein, Human 来源于E. coli,可用作治疗结核病 (TB) 的辅助免疫治疗剂。
  • HY-P7080
    IL-4 Protein, Mouse (CHO)

    rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

    Mouse CHO
    IL-4 Protein, Mouse (CHO)是一种 CHO 细胞来源的特异性细胞因子,促进 B 淋巴细胞的增殖,分化和细胞表面蛋白调节。
  • HY-P7016
    GM-CSF Protein, Human (CHO)

    rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim

    Human CHO
    GM-CSF Protein, Human (CHO)是造血生长因子和免疫调节剂。
  • HY-P7025A
    IFN-gamma Protein, Human (143a.a, CHO)

    重组人干扰素-γ (CHO 细胞表达)

    rHuIFN-γ; IFNG; IFN-gamma; Interferon gamma

    Human CHO
    IFN-gamma Protein, Human (CHO)是一种细胞因子,具有免疫调节作用,可抗病毒、抗肿瘤等。
  • HY-P70543
    TGF beta 1/TGFB1 Protein, Human (112a.a, HEK293)

    人转化生长因子-β1

    Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1

    Human HEK293
    TGF beta 1/TGFB1 蛋白最初被认为是一种诱导啮齿动物成纤维细胞生长的生长因子。TGF beta 1/TGFB1 蛋白可将细胞阻滞在 G1 期。TGF beta 1/TGFB1 是内源性调节细胞凋亡的因子。重组人 TGF beta 1/TGFB1 蛋白 是由 HEK293细胞表达的,A279-S390 片段的蛋白。
  • HY-P7085A
    M-CSF Protein, Mouse (CHO)

    重组小鼠巨噬细胞群刺激因子 (CHO 细胞表达)

    rMuM-CSF; CSF-1; MGI-IM

    Mouse CHO
    M-CSF Protein, Mouse (CHO)是一种促炎性细胞因子,与受体 CSF1R 结合,参与单核/巨噬细胞的增殖,破骨细胞的诱导,在受损的软骨及骨质疏松等疾病中起到重要作用。
  • HY-P70783
    IGF-I/IGF-1 Protein, Human (70a.a, E51R)

    Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

    Human E. coli
  • HY-P7074A
    IL-10 Protein, Mouse (CHO)

    rMuIL-10; CSIF

    Mouse CHO
    IL-10 Protein, Mouse (CHO)是一种有效的 CHO 细胞来源的抗炎细胞因子,作用于感染了神经性冠状病毒的小鼠,增强免疫介导的脱髓鞘作用。
  • HY-P70750G
    GMP IL-4 Protein, Human (HEK293)

    GMP IL-4 蛋白, Human (HEK293)

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human HEK293
    GMP IL-4 蛋白, Human (HEK293) 是一种由 HEK293 细胞产生、GMP 级别的重组蛋白,C 端带有 His 标签。IL-4 是一种抗炎细胞因子,可作为多种免疫和炎症过程的多效调节剂。
  • HY-P70776G
    GMP IL-15 Protein, Human

    Interleukin-15; IL-15; IL15

    Human E. coli
  • HY-P70567G
    GMP GM-CSF Protein, Human (HEK293, His)

    Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin and Sargramostim

    Human HEK293
  • HY-P70755G
    GMP IL-7 Protein, Human (HEK293, His)

    Interleukin-7; IL-7; IL7

    Human HEK293
  • HY-P70787
    IGF-I/IGF-1 Protein, Human (67a.a)

    Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

    Human E. coli
  • HY-P7121
    HGF Protein, Human (CHO)

    重组人肝细胞生长因子 (CHO 细胞表达)

    rHuHGF; Hepatopoietin-A; SF

    Human CHO
    HGF Protein, Human (CHO)是一种细胞因子,能够与 Met 激酶受体结合,具有多种生物活性。
  • HY-P70758
    IL-2 Protein, Human (HEK293, His)

    Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

    Human HEK293
  • HY-P7042
    IL-4 Protein, Human (CHO)

    rHuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

    Human CHO
    IL-4 Protein, Human (CHO)是一种 CHO 细胞来源的有效的淋巴细胞生长因子,刺激 B 细胞增殖分化,参与炎症反应。
  • HY-P7044
    IL-6 Protein, Human

    rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    Human E. coli
    IL-6 Protein, Human 有效诱导肝细胞合成急性期蛋白,参与炎症反应。
目录号 产品名 作用方式 纯度