1. 重组蛋白
  2. GMP-grade Proteins

GMP-grade Proteins  (GMP 级蛋白)

MedChemExpress GMP (生产质量管理规范) 重组蛋白在特定的指导下生产,以确保产品质量和一致性。我们提供的 GMP 级别重组蛋白是在独立的 QA 监督下生产,并具有质量记录和完全可追溯性。

每一批 GMP 级重组蛋白都经过严格的 QC 测试:

•  生物活性验证

•  纯度验证

• 稳定性测试

•  内毒素测试

•  测定分子量 (SDS-PAGE)

•  宿主细胞 DNA 残留含量分析

•  宿主细胞蛋白残留含量分析

•  支原体测试

•  其他测试

MCE GMP 级别重组蛋白能作为原料或辅助试剂、细胞培养或其他体外生物加工。

MedChemExpress GMP (Good Manufacturing Practice) recombinant proteins are manufactured under specific guidelines to ensure product quality and consistency. The use of high-quality media supplements, such as growth factors and cytokines, is essential to ensuring safety, efficacy, and minimizing batch-to-batch variation. We offer GMP-grade recombinant proteins produced with quality documentation and full traceability, under independent QA oversight.

Each lot of our GMP-grade recombinant proteins undergoes rigorous QC testing tests:

•  Biological Activity Validation

•  Purity Testing

•  Stability Testing

•  Endotoxin Testing

•  Molecular weight determination by SDS-PAGE

•  Residual Host Cell DNA Content Analysis

•  Residual Host Cell Protein Content Analysis

•  Mycoplasma Testing

•  Other tests depending on your needs

MCE GMP recombinant proteins can be used as raw materials or ancillary reagents cell culture (expansion, polarization, and differentiation of cells) or other ex vivo bioprocessing.

目录号 产品名 / 同用名 种属 表达系统
  • HY-P70750G
    GMP IL-4 Protein, Human (HEK293)

    GMP IL-4 蛋白, Human (HEK293)

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human HEK293
    GMP IL-4 蛋白, Human (HEK293) 是一种由 HEK293 细胞产生、GMP 级别的重组蛋白,C 端带有 His 标签。IL-4 是一种抗炎细胞因子,可作为多种免疫和炎症过程的多效调节剂。
  • HY-P70776G
    GMP IL-15 Protein, Human

    Interleukin-15; IL-15; IL15

    Human E. coli
  • HY-P70567G
    GMP GM-CSF Protein, Human (HEK293, His)

    Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin and Sargramostim

    Human HEK293
  • HY-P70755G
    GMP IL-7 Protein, Human (HEK293, His)

    Interleukin-7; IL-7; IL7

    Human HEK293
  • HY-P7109G
    GMP EGF Protein, Human

    Pro-epidermal growth factor; EGF; Urogastrone

    Human E. coli
  • HY-P70426G
    GMP TNF-alpha/TNFSF2 Protein, Human

    GMP级重组人 TNF-alpha/TNFSF2 蛋白

    Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; TNF; TNFA; TNFSF2

    Human E. coli
    TNF alpha (肿瘤坏死因子 α) 是一种由 157 个氨基酸组成的同源三聚体蛋白,是一种有效的促炎细胞因子。TNF alpha 与其受体结合,主要是 TNFR1 和 TNFR2 ,然后传递信号以实现炎症和细胞死亡等生物学功能。TNF alpha 通过 TNFR2 受体激活 NF-κB 通路促进癌细胞生长、侵袭和转移,但抗 TNF-α 抗体能显着抑制结肠炎相关癌症 (CAC) 小鼠的肿瘤发展。TNF alpha 作为一种原神经原因子可激活 SAPK/JNK 通路,并能够促进神经元替代和脑修复以应对脑损伤。TNF-alpha/TNFSF2 Protein, Human (Biotinylated, HEK293, His-Avi) 是一种由 HEK293 细胞表达的生物素化的重组蛋白,其 C 末端带有一个 Avi 标签和一个 His 标签,由 157 个 (V77-L233) 氨基酸组成。
  • HY-P7044G
    GMP IL-6 Protein, Human

    Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2

    Human E. coli
  • HY-P70758G
    GMP IL-2 Protein, Human (HEK293, His)

    Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

    Human HEK293
  • HY-P7038G
    GMP IL-21 Protein, Human

    Interleukin-21; IL-21; Za11; IL21

    Human E. coli
  • HY-P70544G
    GMP FLT3LG Protein, Human (HEK293, His)

    Fms-related tyrosine kinase 3 ligand; Flt3L; SL cytokine; FLT3LG

    Human HEK293
  • HY-P70610G
    GMP IFN-gamma Protein, Human (HEK293)

    Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG

    Human HEK293
  • HY-P70783G
    GMP IGF-I/IGF-1 Protein, Human (E51R)

    Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1

    Human E. coli
  • HY-P70543G
    GMP TGF beta 1/TGFB1 Protein, Human (HEK293)

    Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1

    Human HEK293
    TGF beta 1/TGFB1 蛋白最初被认为是一种诱导啮齿动物成纤维细胞生长的生长因子。TGF beta 1/TGFB1 蛋白可将细胞阻滞在 G1 期。TGF beta 1/TGFB1 是内源性调节细胞凋亡的因子。GMP 级重组人 TGF beta 1/TGFB1 蛋白 是由 HEK293 细胞表达的,A279-S390 片段的蛋白。
  • HY-P70576G
    GMP IL-3 Protein, Human (His)

    Interleukin-3; IL-3; Hematopoietic Growth Factor; Mast Cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-Cell-Stimulating Factor; IL3

    Human E. coli
  • HY-P70586G
    GMP IL-1 beta Protein, Human

    重组人细胞介素-1β,GMP级

    Interleukin-1 beta; Catabolin; IL1F2; IL1B

    Human E. coli
    IL-1 beta 是一种强效促炎细胞因子,由单核细胞、巨噬细胞和树突状细胞表达,在炎症和免疫反应中起关键作用。IL-1 beta 以无活性的 pro-IL-1β (由 pro-Il-1b 编码) 形式产生,以响应炎症刺激。GMP IL-1 beta Protein, Human 一种 GMP 级别的重组蛋白,由 153 个氨基酸 (A117-S269) 组成,在大肠杆菌中表达。
  • HY-P70609G
    CD40L/CD154/TRAP Protein, Human (HEK293)

    重组人 CD40L/CD154/TRAP 蛋白 (HEK293)

    CD40 ligand; CD40-L; TRAP; CD154; TNFSF5

    Human HEK293
    CD40L (CD154; TRAP) 是 CD40 (TNFRSF5) 的配体,在 T 细胞中产生共刺激信号而发挥上调 IL-4 合成的作用。CD40L 在活化的 CD4+ T 淋巴细胞上特异性表达,参与 NF-κB/MAPK 信号通路。CD40L 还参与 B 细胞的分化、成熟和凋亡。人 CD40L 蛋白可裂解为 2 种亚型,包括膜状肽 (1-261 a.a.) 和可溶性肽 (113-261 a.a.) (作为整合素的配体)。重组人 CD40L/CD154/TRAP 蛋白 (HEK293) 全长 149 个氨基酸 (M113-L261),由 HEK293 细胞表达,不带标签。
  • HY-P70637G
    GMP TPO/Thrombopoietin Protein, Human (HEK293, His)

    Thrombopoietin; C-mpl ligand; MGDF; THPO

    Human HEK293
  • HY-P70757G
    GMP SCF Protein, Human (HEK293, His)

    Kit Ligand; MGF; SCF; c-Kit ligand; KITLG; sKITLG

    Human HEK293
  • HY-P70760G
    GMP IL-18 Protein, Human (HEK293, His)

    Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma; GIF; IL-18; IL-1g; IL1F4; MGC12320; IL18

    Human HEK293
  • HY-P78549
    GMP IL-4 Protein, Human

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human E. coli
目录号 产品名 作用方式 纯度