1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. Itk

Itk (IL-2诱导的T细胞激酶)

Itk (Interleukin-2-inducible T-cell kinase) is a member of the TEC family of kinases and is highly expressed in T cells. Itk plays a role in T-cell proliferation, differentiation, cytokine release and chemotaxis. Itk is functionally important for the development and effector function of Th2 and Th17 cells. Itk is an attractive target for the treatment of T-cell-mediated inflammatory diseases.

Itk 相关产品 (1):

Cat. No. Product Name Effect Purity
  • HY-128726
    ITK inhibitor 2 Inhibitor
    ITK inhibitor 2 是一种有效的选择性 ITK 抑制剂,IC50值为 2 nM。详细信息请参考专利文献 WO2011065402A1 中的化合物 4。
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