1. 重组蛋白
  2. Ubiquitin Related Proteins
  3. Deubiquitinase

Deubiquitinase  (去泛素化酶)

Deubiquitinating enzymes (DUBs) are a large group of proteases that specifically remove ubiquitin (Ub) or ubiquitin-like proteins (UBLs) from of interest undergoing proteasomal degradation. The DUBs are classified into distinct families based on their sequence similarities and likely mechanisms of action, the vast majority of which are cysteine proteases. These include ubiquitin-specific proteases (USPs), ubiquitin C-terminal hydrolases (UCHs), ovarian tumor proteases (OTUs), Machado-Joseph disease proteases (MJDs), Jab1/Mov34/Mpr1 (JAMM) metalloproteases, and the recently-discovered MIU-containing novel DUB family, (MINDY) proteases. They regulate several cellular functions, including proteasome-dependent and lysosome-dependent proteolysis, gene expression, cell cycle progression, chromosome segregation, kinase activation, apoptosis, localization, DNA repair, maintenance of stemness, spermatogenesis, and degradation of signaling intermediates. (Targeting Deubiquitinase)

目录号 产品名 / 同用名 种属 表达系统
  • HY-P73466
    UCHL1 Protein, Mouse (His)

    Ubiquitin carboxyl-terminal hydrolase isozyme L1; UCH-L1; Uchl1; PGP9.5

    Mouse E. coli
  • HY-P74479
    USP5 Protein, Human (sf9, His)

    Ubiquitin carboxyl-terminal hydrolase 5; Isopeptidase T; USP5; ISOT

    Human Sf9 insect cells
  • HY-P71096
    UCHL1 Protein, Human (His)

    Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1; UCH-L1; Neuron Cytoplasmic Protein 9.5; PGP 9.5; PGP9.5; Ubiquitin Thioesterase L1; UCHL1

    Human E. coli
  • HY-P71418
    USP14 Protein, Human (His)

    Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14; Ubiquitin Thioesterase 14; Ubiquitin-Specific-Processing Protease 14; USP14; TGT

    Human E. coli
  • HY-P74483
    UCHL1 Protein, Rat (His)

    Ubiquitin carboxyl-terminal hydrolase isozyme L1; UCH-L1; Uchl1; PGP9.5

    Rat E. coli
  • HY-P76119
    UCHL3 Protein, Mouse (His)

    Ubiquitin carboxyl-terminal hydrolase isozyme L3; UCH-L3; Ubiquitin thioesterase L3

    Mouse E. coli
  • HY-P77277
    USP46 Protein, Human/Mouse (sf9)

    Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme 46; Usp46

    Human; Mouse Sf9 insect cells
  • HY-P71115
    UCHL3 Protein, Human (His)

    Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3; UCH-L3; Ubiquitin Thioesterase L3; UCHL3

    Human E. coli
  • HY-P71182
    OTUB2 Protein, Human (GST)

    Ubiquitin Thioesterase OTUB2; Deubiquitinating Enzyme OTUB2; OTU Comain-Containing Ubiquitin Aldehyde-Binding Protein 2; Otubain-2; Ubiquitin-Specific-Processing Protease OTUB2; OTUB2; C14orf137; OTB2; OTU2

    Human E. coli
  • HY-P71611
    USP7 Protein, Human (His-SUMO)

    Deubiquitinating enzyme 7; HAUSP; Herpes virus associated ubiquitin specific protease; Herpesvirus-associated ubiquitin-specific protease; TEF 1; tef-1; TEF1; UBP 7; UBP-7; UBP7; UBP7_HUMAN; USP 7; usp-7; Usp7; VMW110-ASSOCIATED PROTEIN, 135-KD

    Human E. coli
  • HY-P74478
    USP7 Protein, Human (sf9)

    Ubiquitin carboxyl-terminal hydrolase 7; USP7; HAUSP

    Human Sf9 insect cells
  • HY-P74480
    USP30 Protein, Human (sf9, SUMO)

    Ubiquitin carboxyl-terminal hydrolase 30; Ub-specific protease 30; USP30

    Human Sf9 insect cells
  • HY-P75952
    OTUB1 Protein, Human (His)

    Ubiquitin thioesterase OTUB1; Otubain-1; OTUB1; OTB1; OTU1

    Human E. coli
  • HY-P76689
    UCHL3 Protein, Rat (His)

    Ubiquitin carboxyl-terminal hydrolase isozyme L3; UCH-L3; Ubiquitin thioesterase L3

    Mouse; Human E. coli
  • HY-P77118
    OTUB2 Protein, Human (His)

    Ubiquitin thioesterase OTUB2; Otubain-2; C14orf137; OTB2; OTU2

    Human E. coli
  • HY-P77278
    USP46 Protein, Human/Mouse (sf9, SUMO)

    Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme 46; Usp46

    Human; Mouse Sf9 insect cells
目录号 产品名 作用方式 纯度