1. 重组蛋白
  2. CD Antigens
  3. T Cell CD Proteins

T Cell CD Proteins  (T 细胞 CD 蛋白)

The cluster of differentiation (CD) antigens a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. The lineage-specific marker for T cells is cytoplasmic CD3, which appears in the earliest T cells as precursors in the thymus. Early T-cell precursors also express CD2 and CD7. During thymic maturation, the T-cell precursor undergoes rearrangements of the T-cell receptor. This process is accompanied by the appearance of other T-cell lineage-associated markers (CD5, CD4, CD8). The majority of the mature T cells are either CD4+ or CD8+. Thymocytes, however, and aberrant neoplastic T cells may coexpress CD4 and CD8 as well as immature T-cell markers TdT and CD1a.

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