2. Signaling Pathways
  3. Stem Cell/Wnt
  4. Oct3/4

Oct3/4 (八聚体结合转录因子3/4)

POU5F1; Slc22a3

Oct3/4 (also known as POU5F1 and Oct4) is regarded as one of the key regulators of pluripotency. Oct-4 is a homeodomain transcription factor of the POU family. This protein is critically involved in the self-renewal of undifferentiated embryonic stem cells. it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely regulated; too much or too little will cause differentiation of the cells.

Oct3/4 相关产品 (6):

目录号 产品名 作用方式 纯度
  • HY-12303
    OAC1 Activator 99.12%
    OAC1 是一种有效的 Oct4 激活剂。OAC1 激活 Oct4 和 Nanog 启动子，促进诱导多功能干细胞 (iPSC) 的形成。OAC1 通过上调 HOXB4 表达激活 OCT4。OAC1 增加了 Oct4-Nanog-Sox2 三联体和 TET1 的转录。OAC1 通过提高效率和缩短重编程时间，促进了细胞的重编程。
  • HY-18772
    O4I2 Activator 99.42%
    O4I2 是有效的 Oct3/4 诱导剂。O4I2 可诱导多能干细胞相关基因 Lin28、Sox2 和 Nanog 的表达，并抑制 Rex1。
  • HY-12884
    OAC2 Activator 99.57%
    OAC2是Oct4激活化合物，其通过Oct4基因启动子激活表达。
  • HY-18773
    Oct3/4-inducer-1 Activator 98.04%
    Oct3/4-inducer-1 (compound 2) 是一种有效的 Oct3/4 诱导剂。Oct3/4-inducer-1 促进 Oct3/4 的表达和稳定，增强其在多种人体细胞中的转录活性。
  • HY-18771
    O4I1 Activator
    O4I1是一种有效的Oct3/4诱导剂。
  • HY-119672
    Oct4 inducer-1 Activator 98.27%
    Oct4 inducer-1 (compound OAC-3) 是一种有效的 Oct4 激活剂。Oct4 inducer-1 激活 Oct4 和 Nanog 启动子，促进诱导多能干细胞 (iPSC) 的形成。Oct4 inducer-1 通过提高效率和缩短重编程时间，促进了细胞的重编程。