1. Signaling Pathways
  2. Stem Cell/Wnt
  3. Oct3/4

Oct3/4 (八聚体结合转录因子3/4)

POU5F1; Slc22a3

Oct3/4 (also known as POU5F1 and Oct4) is regarded as one of the key regulators of pluripotency. Oct-4 is a homeodomain transcription factor of the POU family. This protein is critically involved in the self-renewal of undifferentiated embryonic stem cells. it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely regulated; too much or too little will cause differentiation of the cells.

Oct3/4 相关产品 (8):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-12303
    OAC1 Activator 99.56%
    OAC1 是一种有效的 Oct4 激活剂。OAC1 激活 Oct4 和 Nanog 启动子,促进诱导多功能干细胞 (iPSC) 的形成。OAC1 通过上调 HOXB4 表达激活 OCT4。OAC1 增加了 Oct4-Nanog-Sox2 三联体和 TET1 的转录。OAC1 通过提高效率和缩短重编程时间,促进了细胞的重编程。
    OAC1
  • HY-18772
    O4I2 Activator 99.30%
    O4I2 是有效的 Oct3/4 诱导剂。O4I2 可诱导多能干细胞相关基因 Lin28Sox2Nanog 的表达,并抑制 Rex1
    O4I2
  • HY-12884
    OAC2 Activator 98.10%
    OAC2是Oct4激活化合物,其通过Oct4基因启动子激活表达。
    OAC2
  • HY-18771
    O4I1 Activator 98.05%
    O4I1是一种有效的Oct3/4诱导剂。
    O4I1
  • HY-18773
    Oct3/4-inducer-1 Activator 98.04%
    Oct3/4-inducer-1 (compound 2) 是一种有效的 Oct3/4 诱导剂。Oct3/4-inducer-1 促进 Oct3/4 的表达和稳定,增强其在多种人体细胞中的转录活性。
    Oct3/4-inducer-1
  • HY-B0380A
    Trimebutine maleate

    马来酸曲美布汀

    99.79%
    Trimebutine maleate 是一种口服活性的抗癌剂。Trimebutine maleate 选择性地抑制卵巢癌干细胞 (CSCs) 的干性和增殖,降低结肠肌肉的高收缩性,调节胃肠道蠕动,诱导凋亡,并且可用于胶质瘤/胶质母细胞瘤和肠易激综合征的研究。
    Trimebutine maleate
  • HY-119672
    Oct4 inducer-1 Activator 98.27%
    Oct4 inducer-1 (compound OAC-3) 是一种有效的 Oct4 激活剂。Oct4 inducer-1 激活 Oct4 和 Nanog 启动子,促进诱导多能干细胞 (iPSC) 的形成。Oct4 inducer-1 通过提高效率和缩短重编程时间,促进了细胞的重编程。
    Oct4 inducer-1
  • HY-154951
    Oct4 inducer-2 Inducer
    Oct4 inducer-2 是一种 OCT4 诱导剂,通过促进内源性 OCT4 的表达来维持 hiPSC 的形成,可用于抗衰老研究。
    Oct4 inducer-2