2. 重组蛋白
  3. Enzymes & Regulators
  4. Ligases (EC 6)

Ligases (EC 6)  (连接酶)

酶可以根据反应和底物特异性的不同以及作用机制进行系统的分类。连接酶 (EC 6.x.x.x) 是一类酶，催化两个大分子，如蛋白质或多肽，通过建立新的化学键 (如 C-O、C-N、C-S 键) 连接的反应。 连接酶又被进一步划分为六类连接酶: 1) EC 6.1形成碳-氧键的连接酶; 2) EC 6.2 形成碳-硫键的连接酶; 3) EC 6.3形成碳-氮键的连接酶; 4) EC 6.4形成碳-碳键连接酶; 5) EC 6.5 建立磷酸-酯键的连接酶; 6) EC 6.6建立氮-金属键的连接酶。 DNA一种常见的连接酶，常用于分子生物学实验中的 DNA片段连接。

Enzymes can be classified systematically according to the difference between reaction and substrate specificity, and the mechanism of action. Ligases (EC 6.x.x.x) are a group of enzymes that catalyze the reaction of joining two large molecules (such as proteins or peptides) by establishing a new chemical bond, for instance C-O, C-N, C-S bonds. Ligases are further divided into six subclasses: 1) EC 6.1 ligases establishing carbon-oxygen bonds; 2) EC 6.2 ligases establishing carbon-sulfur bonds; 3) EC 6.3 ligases establishing carbon-nitrogen bonds; 4) EC 6.4 ligases establishing carbon-carbon bonds; 5) EC 6.5 ligases establishing phosphoric-ester bonds; and 6) EC 6.6 ligases establishing nitrogen-metal bonds. DNA ligase is a common ligase which often used in molecular biology laboratories to join DNA fragments.

目录号 产品名 / 同用名 种属 表达系统
  • HY-P70840
    KARS Protein, Human (HEK293, His)

    Lysine--tRNA Ligase; Lysyl-tRNA Synthetase; LysRS; KARS; KIAA0070

    		Human HEK293
  • HY-P70294
    Glutamine synthetase/GLUL Protein, Human (His)

    rHuGlutamine synthetase/GLUL, His; Glutamine Synthetase; GS; Glutamate Decarboxylase; Glutamate--Ammonia Ligase; GLUL; GLNS

    		Human E. coli
  • HY-P70360
    Glutathione synthetase/GSS Protein, Human (His)

    rHuGlutathione synthetase/GSS, His; Glutathione Synthetase; GSH Synthetase; GSH-S; Glutathione Synthase; GSS

    		Human E. coli
  • HY-P71445
    CPS1/CPSase I Protein, Human (His)

    Carbamoyl phosphate synthase; Carbamoyl phosphate synthase mitochondrial; Carbamoyl phosphate synthase; Carbamoyl phosphate synthetase 1; Carbamoyl phosphate synthetase 1 mitochondrial; Carbamoyl phosphate synthetase I; Carbamoyl-phosphate synthase [ammonia]; Carbamoyl-phosphate synthetase I; Carbamoylphosphate synthase; Carbamoylphosphate synthetase 1; Carbamoylphosphate synthetase I; CPS 1; Cps1; CPSase 1; CPSase I; CPSASE1; mitochondrial; MS738

    		Human E. coli
  • HY-P71511
    Gamma-GCS Protein, E.coli (His-SUMO)

    gshA; gsh-I; b2688; JW2663Glutamate--cysteine ligase; EC 6.3.2.2; Gamma-ECS; GCS; Gamma-glutamylcysteine synthetase

    		E.coli E. coli
  • HY-P71538
    AIMP2 Protein, Human (His)

    Aimp2; AIMP2_HUMAN; Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 ; ARS interacting multi functional protein 2 ; JTV 1; JTV 1 protein; JTV1; JTV1 gene; Multisynthase complex auxiliary component p38; Multisynthetase complex auxiliary component p38; P38; PRO0992; Protein JTV 1; Protein JTV-1; tRNA SYNTHETASE COFACTOR p38

    		Human E. coli
    AIMP2 Protein, Human (His) 在 α-突触核蛋白 (aSyn) 聚集中起主要作用。
  • HY-P71642
    Acetyl-CoA synthetase 1/AceCS Protein, Mouse (His)

    乙酰辅酶 A 合成酶 1/AceCS 蛋白，小鼠 (His)

    Acss2; Acas2; Acecs1Acetyl-coenzyme A synthetase; cytoplasmic; EC 6.2.1.1; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1

    		Mouse E. coli
    Acetyl-CoA synthetase 1/AceCS Protein, Mouse (His) 是一种将乙酸转化为乙酰辅酶 A 的酶，通过在压力条件下捕获乙酸作为碳源为肿瘤细胞提供乙酰辅酶 A。
  • HY-P73933
    HARS/HisRS Protein, Human (sf9, His)

    Histidine--tRNA ligase, cytoplasmic; HisRS; HARS1; HARS; HRS

    		Human Sf9 insect cells
  • HY-P74128
    GARS Protein, Human (sf9, His)

    Glycine--tRNA ligase; GlyRS; GARS1; GARS

    		Human Sf9 insect cells
  • HY-P74435
    AACS Protein, Human (sf9, His)

    Acetoacetyl-CoA synthetase; AACS; ACSF1

    		Human Sf9 insect cells
  • HY-P75309
    DARS Protein, Human (His)

    Aspartate--tRNA ligase, cytoplasmic; AspRS; DARS1; PIG40

    		Human E. coli
  • HY-P75475
    BirA Protein, E. coli (His-MBP)

    Bifunctional ligase/repressor BirA; birA; bioR; dhbB

    		E.coli E. coli
  • HY-P75517
    Alanyl-tRNA synthetase Protein, Human (sf9, His)

    Alanine--tRNA ligase, cytoplasmic; AlaRS; AARS1; AARS

    		Human Sf9 insect cells
  • HY-P7613
    ASS1 Protein, Human (His)

    rHuASS1, His; Argininosuccinate Synthase; Citrulline--Aspartate Ligase; ASS1; ASS

    		Human E. coli
    ASS1 Protein, Human (His)是一种在 E. coli 中表达的，末端有 His 标签的重组人 Argininosuccinate synthase。Argininosuccinate synthase 是一种酶，催化瓜氨酸和天冬氨酸合成精氨酸琥珀酸酯。
  • HY-P75567
    AARS1 Protein, Mouse (sf9, His)

    Alanine--tRNA ligase, cytoplasmic; Alanyl-tRNA synthetase; AlaRS; Sti; Aars

    		Mouse Sf9 insect cells
目录号 产品名 作用方式 纯度