1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Kinesin

Kinesin (驱动蛋白)

Kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule filaments, and are powered by the hydrolysis of ATP (thus kinesins are ATPases). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo. Most kinesins walk towards the plus end of a microtubule, entails transporting cargo from the centre of the cell towards the periphery. Kinesins were discovered as microtubule (MT)-based anterograde intracellular transport motors. The founding member of this superfamily, the genomes of mammals encode more than 40 kinesin proteins, organized into at least 14 families named kinesin-1 through kinesin-14.

Kinesin Isoform Specific Products:

  • Kinesin-5/Eg5/KSP

  • Kinesin-6

  • Kinesin-7/CENP-E

  • Kinesin-12

  • Kinesin-14

Kinesin 相关产品 (11):

Cat. No. Product Name Effect Purity
  • HY-15948
    Kif15-IN-1 Inhibitor 99.53%
    Kif15-IN-1 是一种驱动蛋白家族 15 (Kif15) 的抑制剂,主要用于细胞增殖性疾病的研究。
  • HY-101071A
    Monastrol Inhibitor 99.95%
    Monastrol是具有高效性和细胞渗透性的有丝分裂驱动蛋白 Eg5 的抑制剂,IC50 值为 14 μM。
  • HY-12241
    AZ82 Inhibitor 99.08%
    AZ82 是一种驱动蛋白样蛋白 KIFC1 (HSET/KIFC1) 的选择性抑制剂,其 Ki 值和 IC50 值分别为 43 nM 和 300 nM。
  • HY-101298
    Paprotrain Inhibitor 99.54%
    Paprotrain是可渗透细胞的kinesin MKLP-2 的抑制剂,抑制 MKLP-2 的 ATPase 活性,IC50 值为 1.35 μM,Ki 值为 3.36 μM,同时对 DYRK1A 有中等的抑制作用,IC50值为 5.5 μM。
  • HY-14846
    Litronesib Inhibitor 99.59%
    Litronesib (LY2523355) 是一种选择性的有丝分裂特异性运动蛋白 Eg5 抑制剂,具有抗肿瘤的活性。
  • HY-12069
    SB-743921 Inhibitor 98.11%
    SB-743921 是一种有效的驱动蛋白 (Eg5) 抑制剂,Ki 值为 0.1 nM。
  • HY-19530
    PF-2771 Inhibitor 99.56%
    PF-2771 是一种选择性的着丝粒蛋白 E (CENP-E) 抑制剂,IC50 值为 16.1 nM,具有抗肿瘤活性。
  • HY-15857
    CW-069 Inhibitor 99.75%
    CW-069 是一种微管运动蛋白 HSET 的别构抑制剂,IC50 值为 75 μM。
  • HY-19944
    Dimethylenastron Inhibitor 98.24%
    Dimethylenastron 是一种有效的驱动蛋白 Eg5 抑制剂,IC50 值为 200 nM。
  • HY-14846A
    Litronesib Racemate 99.20%
    Litronesib Racemate (LY2523355 Racemate) 是 litronesib 的外消旋体。Litronesib 是选择性的驱动蛋白 Eg5 别构抑制剂。
  • HY-15949
    Kif15-IN-2 Inhibitor 98.64%
    Kif15-IN-2 是一种驱动蛋白 Kif15 的抑制剂,主要用于细胞增殖性疾病的研究。
Isoform Specific Products

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Please try each isoform separately.