1. 重组蛋白
  2. CD Antigens
  3. B Cell CD Proteins

B Cell CD Proteins  (B 细胞 CD 蛋白)

The cluster of differentiation (CD) antigens a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. The B-cell precursors express cytoplasmic CD22 and CD79 in early, while surface CD19 and CD10 appear later. With increased differentiation there is gradual decrease in CD10 and gradual gain in CD20. CD10, however, appears again in follicular center cells (FCCs) in the lymph nodes and the spleen. Normal mature B cells express surface immunoglobulin as well as CD19, CD20, and CD22.

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