2. 重组蛋白
  3. CD Antigens
  4. B Cell CD Proteins

B Cell CD Proteins  (B 细胞 CD 蛋白)

The cluster of differentiation (CD) antigens a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. The B-cell precursors express cytoplasmic CD22 and CD79 in early, while surface CD19 and CD10 appear later. With increased differentiation there is gradual decrease in CD10 and gradual gain in CD20. CD10, however, appears again in follicular center cells (FCCs) in the lymph nodes and the spleen. Normal mature B cells express surface immunoglobulin as well as CD19, CD20, and CD22.

 
目录号 产品名 / 同用名 种属 表达系统
  • HY-P73499
    CD40 Protein, Human (193a.a, HEK293, His)

    Tumor Necrosis Factor Receptor Superfamily member 5; Bp50; CD40L Receptor; CDw40; TNFRSF5

    		Human HEK293
  • HY-P70731
    CD38 Protein, Human (HEK293, His)

    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule; CD38

    		Human HEK293
  • HY-P70629
    IL-2R alpha Protein, Human (HEK293, Fc)

    IL-2R alpha; IL-2RA; IL-2 R alpha; Interleukin-2 receptor subunit alpha; CD25; p55; TAC antigen; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL-2 receptor subunit alpha

    		Human HEK293
    IL-2R alpha Protein, Human (HEK293, Fc)是一种由 HEK293 细胞表达的，C 末端有 Fc 片段的重组人IL-2RA。IL-2RA 是白细胞介素-2 受体的一个亚单位，通过调节 IL-2R 对配体的亲和力，在调节 IL-2 介导的反应中发挥着重要作用。
  • HY-P7374
    IL-2R alpha/CD25 Protein, Human (HEK293, Fc)

    重组人 IL-2R alpha/CD25 蛋白 (HEK293, Fc)

    rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R alpha; IL-2Rα; IL2RA

    		Human HEK293
    IL-2R alpha (CD25) 是高亲和力 IL-2 受体的重要组成部分。IL-2R alpha 增强 IL-2 与其受体复合物的结合，从而调节 T 细胞生长和其他淋巴功能。IL-2R alpha/CD25 Protein, Human (HEK293, Fc) 是一种重组人 IL-2R alpha 蛋白，在 HEK293 细胞中表达，由 192 个氨基酸组成 (E22-C213)，C 末端带有hFc 标签。
  • HY-P7003
    BAFF/TNFSF13B Protein, Human (CHO)

    重组人 B 细胞激活因子/TNFSF13B (CHO 细胞表达)

    rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20

    		Human CHO
    BAFF/TNFSF13B Protein, Human (CHO)是肿瘤坏死因子超家族的一员，在外周 B 细胞内稳态中具有重要作用。
  • HY-P7168
    Fas/CD95 Protein, Human (HEK293)

    重组人 Fas/CD95 蛋白 (HEK293)

    rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; FAS1; Apo-1

    		Human HEK293
    Fas 受体是一种细胞表面死亡受体，又称凋亡介导表面抗原 Fas 和 Apo-1 抗原。Fas 受体与 Fas 配体结合而形成死亡诱导信号复合物，如 Fas 相关死亡结构域蛋白 (FADD)。Fas 受体参与 caspase 级联反应，调节下游 JNK 和 p38-K 的激活。它还介入 ERK/JNK MAPKs 信号级联，激活 MAPK3/ERK1, MAPK8/JNK 和 NF-κB，与多种恶性肿瘤和免疫系统疾病的发病机制有关。人 Fas 受体含有一个死亡结构域 (230-314 a.a.)，在调节程序性死亡中发挥关键作用。重组人 Fas/CD95 蛋白 (HEK293) 全长 157 个氨基酸 (Q26-S172)，由 HEK293 细胞表达，不带标签。
  • HY-P70428
    BAFF/TNFSF13B Protein, Human (HEK293, His)

    重组人 BAFF/TNFSF13B 蛋白 (HEK293, His)

    Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1

    		Human HEK293
    BAFF/TNFSF13B，是激活B细胞的细胞因子，属于肿瘤坏死因子家族。BAFF 参与癌症免疫，主要在髓系细胞中表达。它的过度表达可导致自身免疫，如系统性红斑狼疮 (SLE)。此外，BAFF 还参与了脂肪形成、动脉粥样硬化、神经炎症过程和缺血再灌注 (I/R) 损伤。人的 BAFF 蛋白有 2 个糖基化结构域和 1 个跨膜结构域 (48-68 a.a.)，可裂分为膜型肽片段和可溶性肽片段。重组人 BAFF/TNFSF13B 蛋白 (HEK293, Fc) 是 BAFF 蛋白的胞外部分 (A134-L285)，由 HEK293 细胞表达，带有 N 端 6*His 标签。
  • HY-P70559
    Siglec-2/CD22 Protein, Human (668a.a, HEK293, His)

    B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22 molecule; CD22; sialic acid binding Ig-like lectin 2; Siglec-2; SIGLEC2FLJ22814; T-cell surface antigen Leu-14

    		Human HEK293
  • HY-P70651
    B7-1/CD80 Protein, Human (208a.a, HEK293, His)

    CD80; Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80

    		Human HEK293
  • HY-P70720
    CD24 Protein, Human (S44T, HEK293, Fc)

    Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A

    		Human HEK293
  • HY-P70762
    CD28 Protein, Human/Cynomolgus (HEK 293, Fc)

    CD28; CD28 antigen; CD28 molecule; T-cell-specific surface glycoprotein CD28; Tp44; TP44

    		Human; Cynomolgus HEK293
  • HY-P72019
    Siglec-2/CD22 Protein, Human (HEK293, His)

    B-cell receptor CD22; BL-CAM; Siglec-2; CD22; SIGLEC2

    		Human HEK293
  • HY-P7215
    IL-2R alpha/CD25 Protein, Human (191a.a, HEK293, His)

    重组人 IL-2R alpha/CD25 蛋白 (191a.a, HEK293, His)

    rHuIL-2Rα, His; TAC-antigen; CD25

    		Human HEK293
    IL-2R alpha (CD25) 是高亲和力 IL-2 受体的重要组成部分。IL-2R alpha 增强 IL-2 与其受体复合物的结合，从而调节 T 细胞生长和其他淋巴功能。IL-2R alpha/CD25 Protein, Human (191a.a, HEK293, His) 是一种重组人 IL-2R alpha 蛋白，在 HEK293 细胞中表达，由 191 个氨基酸组成 (L23-C213)，C 末端带有 His 标签。
  • HY-P72351
    Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His-Avi)

    B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22; T-cell surface antigen Leu-14

    		Human HEK293
  • HY-P72352
    CD24 Protein, Human (Biotinylated, HEK293, Fc-Avi)

    Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A

    		Human HEK293
  • HY-P72353
    CD28 Protein, Human/Cynomolgus (Biotinylated, HEK293, Fc-Avi)

    CD28; CD28 antigen; CD28 molecule; T-cell-specific surface glycoprotein CD28; Tp44; TP44

    		Human; Cynomolgus HEK293
  • HY-P72356
    CD38 Protein, Human (Biotinylated, HEK293, His-Avi)

    ADP-ribosyl cyclase1; 2'-phospho-ADP-ribosyl cyclase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1

    		Rat HEK293
  • HY-P72838
    B7-1/CD80 Protein, Human (HEK293, His-Fc)

    T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; B7; CD80; CD28LG; LAB7

    		Human HEK293
  • HY-P72847
    BCMA/TNFRSF17 Protein, Human (HEK293, His)

    重组人 BCMA/TNFRSF17 蛋白 (HEK293, His)

    Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA

    		Human HEK293
    B Cell Maturation Antigen (BCMA) 也称为 TNFRSF17 或 CD269，是肿瘤坏死因子受体 (TNFR) 超家族的跨膜糖蛋白成员。BCMA 用作多发性骨髓瘤 (MM) 的生物标志物。BCMA 主要在 B 细胞增殖、存活以及分化为浆细胞方面发挥重要作用。BCMA/TNFRSF17 Protein, Human (HEK293, His) 是一种由 HEK293 细胞表达重组蛋白，其 C 末端带有 His 标签，由 54 (M1-A54) 个氨基酸组成。
  • HY-P72890
    CD21 Protein, Human (971a.a, HEK293, His)

    Complement receptor type 2; Cr2; EBV receptor; CD21; C3DR

    		Human HEK293
目录号 产品名 作用方式 纯度