2. 重组蛋白
  3. Ubiquitin Related Proteins
  4. Ubiquitin Enzymes

Ubiquitin Enzymes  (泛素酶)

Ubiquitination is a tightly controlled three-step multienzyme cascades. A ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin ligase (E3) act in a concerted manner to form a covalent bond between ubiquitin and its substrate protein, and thereby write the ubiquitin code. In detail, this process is initiated by a family of mechanistically and structurally-related E1 enzymes. The E1s serve to activate ubiquitin/UBLs through C-terminal adenylation and thiol transfer and to coordinate the utilization of ubiquitin/UBLs in specific downstream pathways by charging cognate E2 enzymes, which then interact with the downstream ubiquitylation machinery to coordinate modification of the target.

 
目录号 产品名 / 同用名 种属 表达系统
  • HY-P76007
    RNF43 Protein, Human (HEK293, Fc)

    E3 ubiquitin-protein ligase RNF43; RING finger protein 43; RNF43

    		Human HEK293
  • HY-P71398
    UBE2B Protein, Human (HEK293, His)

    Ubiquitin-Conjugating Enzyme E2 B; RAD6 Homolog B; HR6B; hHR6B; Ubiquitin Carrier Protein B; Ubiquitin-Conjugating Enzyme E2-17 kDa; Ubiquitin-Protein Ligase B; UBE2B; RAD6B

    		Human HEK293
  • HY-P73485
    XIAP Protein, Human (Avi)

    E3 ubiquitin-protein ligase XIAP; ILP; IAP-3; XIAP; API3; BIRC4

    		Human E. coli
  • HY-P73537
    XIAP Protein, Human (His)

    E3 ubiquitin-protein ligase XIAP; ILP; IAP-3; XIAP; API3; BIRC4

    		Human E. coli
  • HY-P74485
    UBA1 Protein, Human (sf9, His-GST)

    Ubiquitin-like modifier-activating enzyme 1; Protein A1S9; UBA1; A1S9T; UBE1

    		Human Sf9 insect cells
  • HY-P75968
    PDHA1 Protein, Human (sf9, His-GST)

    Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; PDHE1-A type I; PDHA1; PHE1A

    		Human Sf9 insect cells
  • HY-P7617
    ATG3 Protein, Human

    rHuATG3; Ubiquitin-like-conjugating enzyme ATG3; Autophagy-related protein 3; APG3-like; ATG3; APG3; APG3L

    		Human E. coli
    ATG3 Protein, Human是一种在 E. coli 中表达的重组人 Ubiquitin-like-conjugating Enzyme ATG3。ATG3 是用于 LC3 脂化过程的 E2 泛素结合酶，对于自噬至关重要。
  • HY-P71399
    UBE2D1 Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 D1; Stimulator of Fe transport; SFT; UBC4/5 homolog; UbcH5; Ubiquitin carrier protein D1; Ubiquitin-conjugating enzyme E2(17)KB 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-protein ligase D1; SFT; UBC5A; UBCH5; UBCH5A

    		Human E. coli
  • HY-P71395
    UBA5 Protein, Human (His)

    Ubiquitin-like modifier-activating enzyme 5; ThiFP1; UFM1-activating enzyme; Ubiquitin-activating enzyme E1 domain-containing protein 1; UBE1DC1; UBA5

    		Human E. coli
  • HY-P70998
    UBE2D3 Protein, Human

    Ubiquitin-conjugating enzyme E2 D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2(17)KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3; UBE2D3 and UBCH5C.

    		Human E. coli
  • HY-P71020
    UBE2L6 Protein, Human (His)

    Ubiquitin/ISG15-Conjugating Enzyme E2 L6; Retinoic Acid-Induced Gene B Protein; RIG-B; UbcH8; Ubiquitin Carrier Protein L6; Ubiquitin-Protein Ligase L6; UBE2L6; UBCH8

    		Human E. coli
  • HY-P71396
    UBAP1 Protein, Human (His)

    Ubiquitin-Associated Protein 1; UBAP-1; Nasopharyngeal Carcinoma-Associated Gene 20 Protein; UBAP1

    		Human E. coli
  • HY-P71397
    UBE2A Protein, Human (GST-His)

    Ubiquitin-Conjugating Enzyme E2 A; RAD6 Homolog A; HR6A; hHR6A; Ubiquitin Carrier Protein A; Ubiquitin-Protein Ligase A; UBE2A; RAD6A

    		Human E. coli
  • HY-P71400
    UBE2D4 Protein, Human (GST)

    Ubiquitin-Conjugating Enzyme E2 D4; HBUCE1; Ubiquitin Carrier Protein D4; Ubiquitin-Protein Ligase D4; UBE2D4; UBCH5D

    		Human E. coli
  • HY-P71401
    UBE2G2 Protein, Human (GST)

    Ubiquitin-Conjugating Enzyme E2 G2; Ubiquitin Carrier Protein G2; Ubiquitin-Protein Ligase G2; UBE2G2

    		Human E. coli
  • HY-P71402
    UBE2H Protein, Human (GST)

    Ubiquitin-Conjugating Enzyme E2 H; UbcH2; Ubiquitin Carrier Protein H; Ubiquitin-Conjugating Enzyme E2-20K; Ubiquitin-Protein Ligase H; UBE2H

    		Human E. coli
  • HY-P71403
    UBE2I Protein, Human (GST)

    SUMO-Conjugating Enzyme UBC9; SUMO-Protein Ligase; Ubiquitin Carrier Protein 9; Ubiquitin Carrier Protein I; Ubiquitin-Conjugating Enzyme E2 I; Ubiquitin-Protein Ligase I; p18; UBE2I; UBC9; UBCE9

    		Human E. coli
  • HY-P71404
    UBE2J2 Protein, Human (GST)

    Ubiquitin-Conjugating Enzyme E2 J2; Non-Canonical Ubiquitin-Conjugating Enzyme 2; NCUBE-2; UBE2J2; NCUBE2

    		Human E. coli
  • HY-P71405
    UBE2K Protein, Human (GST)

    Ubiquitin-Conjugating Enzyme E2 K; Huntingtin-Interacting Protein 2; HIP-2; Ubiquitin Carrier Protein; Ubiquitin-Conjugating Enzyme E2-25 kDa; Ubiquitin-Conjugating Enzyme E2(25K); Ubiquitin-Conjugating Enzyme E2-25K; Ubiquitin-Protein Ligase; UBE2K; HIP2; LIG

    		Human E. coli
  • HY-P71406
    UBE2M Protein, Human

    NEDD8-conjugating enzyme Ubc12; NEDD8 carrier protein; NEDD8 protein ligase; Ubiquitin-conjugating enzyme E2 M; UBC12; UBE2M;

    		Human E. coli
目录号 产品名 作用方式 纯度