2. 重组蛋白
  3. Enzymes & Regulators
  4. Lyases (EC 4)

Lyases (EC 4)  (裂解酶)

酶可以根据反应和底物特异性的不同以及作用机制进行系统的分类。裂解酶 (EC 4.x.x.x) 是一组酶，通过水解和氧化以外的方法催化 C-C、C-O、C-N 和其他键的裂解，或相反地在双键上添加一个基团。裂解酶与其他酶的不同之处在于，它在一个方向上的反应只需要一个底物，而在逆反应中则需要两个底物。常见的裂解酶有脱羧酶、醛糖酶和脱水酶等。裂解酶可进一步分为七个亚类。 EC 4.1 亚类裂解碳碳键；EC 4.2 亚类裂解碳氧键；EC 4.3 亚类裂解碳氮键；EC 4.1 亚类裂解碳硫键；EC 4.5亚类裂解碳卤键；EC 4.5 亚类断裂磷氧键；EC 4.99包括其他裂解酶。

Enzymes can be classified systematically according to the difference between reaction and substrate specificity, and the mechanism of action. Lyases (EC 4.x.x.x) are a group of enzymes that catalyze the cleavage of C-C, C-O, C-N and other bonds by methods other than hydrolysis and oxidation, or conversely add a group to a double bond. Lyases differ from other enzymes in that they require only one substrate for the reaction in one direction, which differs from other enzymes, but two substrates for the reverse reaction. Common lyases include decarboxylases, aldolases and dehydratases, etc. Lyases can be further classified into seven subclasses. Lyases in EC 4.1 cleave carbon-carbon bonds；EC 4.2 of lyases that break carbon-oxygen bonds；EC 4.3 of lyases cleave carbon-nitrogen bonds; Lyases in EC 4.1 split carbon-sulfur bonds; Lyases in EC 4.5 cleave carbon-halide bonds; Lyases in EC 4.5 fracture phosphorus-oxygen bonds; EC 4.99 includes other lyases.

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