1. Screening Libraries

Screening Libraries  -  化合物库

化合物库作为药物筛选的重要工具,决定了小分子药物研发的速度和质量。作为全球领先的化合物供应商,MCE 可提供活性化合物库、类药多样性库、虚拟筛选数据库等 170 余种化合物库,化合物总数约 1600 万,每种化合物均有详尽的生物活性数据和(或)清晰准确的理化结构信息。这些高质量化合物库可用于高通量筛选(HTS)、高内涵筛选(HCS)、虚拟筛选(VS),是进行新药研发及新适应症探索的专业工具。

• 活性化合物库:可提供 110+ 种即用型化合物库,包含 15,000+ 种具有明确报道的、活性已知、靶点明确的小分子化合物及 17,000+ 种片段化合物。

• 类药多样性库:包括MCE 50K Diversity Library(含 50,000 种化合物)、MCE 5K Scaffold Library(含 5,000 种化合物),具备新颖性、类药性、多样性等多重性质。

• 虚拟筛选数据库:50+ 种,含约 1600 万化合物,数量大,结构多样性丰富。

• 此外,MCE 还提供化合物库定制化服务。您可以根据实验需求选择不同的化合物种类,规格,包装以及化合物排布。

Download

Library Catalog

PDF 1.64 MB

定制您的专属化合物库:

您可以选择:
特定的化合物
规格
96 或 384 孔板布局
浓度
形式 (干粉 或 DMSO溶液)

Compound Screening Libraries
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  • HY-L001 生物活性化合物库
    Bioactive Compound Library
    The large and comprehensive compound library. 16214 compounds
    HY-L001P 生物活性化合物库 Plus
    Bioactive Compound Library Plus
    Bioactive compound library with more novel or rare molecules added. 18426 compounds
    HY-L099 靶点多样性化合物库
    Targeted Diversity Library
    Compound library containing compounds that have been focused against various biological targets. 2380 compounds
    HY-L111 新颖已知活性化合物库
    Novel Bioactive Compound Library
    Compound Library containing a variety of novel bioactive compounds. 1182 compounds
  • HY-L901 50K Diversity Library
    50K Diversity Library
    Representative diversity set and an ideal starting library for phenotypic and target-based HTS. 50000 compounds
    HY-L902 5K Scaffold Library
    5K Scaffold Library
    An exceptionally diverse library. Each compound represents one unique scaffold. 5000 compounds
  • HY-L066 FDA 上市及药典收录化合物库
    FDA Approved & Pharmacopeial Drug Library
    Compound library containing approved drugs and pharmacopoeia collected compounds. 3257 compounds
    HY-L022P FDA 上市库 Plus
    FDA-Approved Drug Library Plus
    Compound library containing marketed drugs approved by FDA, EMA, etc. 2914 compounds
    HY-L022 FDA 上市库
    FDA-Approved Drug Library
    Compound library containing marketed drugs approved by FDA, EMA, etc. 2676 compounds
    HY-L022M FDA 上市库 Mini
    FDA-Approved Drug Library Mini
    The Mini version of FDA-Approved Drug Library for better convenience. 2676 compounds
    HY-L053 NMPA 上市药物库
    NMPA-Approved Drug Library
    Compound library containing marketed drugs approved by NMPA. 1229 compounds
    HY-L026P 临床化合物库 Plus
    Clinical Compound Library Plus
    Compound library containing bioactive molecules that have been only used in clinical trials but not as drugs. 2202 compounds
    HY-L026 临床化合物库
    Clinical Compound Library
    Compound library containing bioactive molecules that have been only used in clinical trials but not as drugs. 1934 compounds
    HY-L035P 老药新用化合物库 Plus
    Drug Repurposing Compound Library Plus
    Compound library containing bioactive molecules that used for drug repurposing. 4609 compounds
    HY-L035 老药新用化合物库
    Drug Repurposing Compound Library
    Compound library containing bioactive molecules that used for drug repurposing. 4159 compounds
    HY-L104 儿童药物库
    Children’s Drug Library
    Compound library containing approved and clinical children’s drugs. 625 compounds
    HY-L116 EMA批准上市药物库
    EMA-Approved Drug Library
    Compound library containing variety of EMA-approved drugs. 614 compounds
    HY-L112 化疗药物库
    Chemotherapy Drug Library
    Compound library containing all kinds of chemotherapeutics. 96 compounds
  • HY-L059 细胞焦亡化合物库
    Pyroptosis Compound Library
    Compound library targeting pyroptosis signaling pathways and related proteins. 1009 compounds
    HY-L051 铁死亡化合物库
    Ferroptosis Compound Library
    Compound library targeting ferroptosis signaling pathways. 746 compounds
    HY-L003 细胞凋亡化合物库
    Apoptosis Compound Library
    Compound library targeting apoptotic signaling pathways and related proteins. 1835 compounds
    HY-L029 自噬化合物库
    Autophagy Compound Library
    Compound library targeting autophagy regulations. 1225 compounds
    HY-L133 铜死亡化合物库
    Cuproptosis Compound Library
    Compound library containing a variety of Cuproptosis related compounds. 156 compounds
  • HY-L064 谷氨酰胺代谢化合物库
    Glutamine Metabolism Compound Library
    Compound library containing a variety of glutamine metabolism compounds. 753 compounds
    HY-L091 脂代谢化合物库
    Lipid Metabolism Compound Library
    Compound library containing all kind of small molecules associated with lipid metabolism. 519 compounds
    HY-L092 糖代谢化合物库
    Glucose Metabolism Compound Library
    Compound library containing all kind of small molecules associated with glucose metabolism. 820 compounds
    HY-L030 人内源性代谢物库
    Human Endogenous Metabolite Compound Library
    Compound library containing Endogenous Metabolites from human issues. 892 compounds
    HY-L123 人代谢物库
    Human Metabolite Library
    Compound library containing all kinds of human metabolites. 4856 compounds
    HY-L084 微生物代谢物库
    Microbial Metabolite Library
    Compound library containing all kind of microbial metabolites. 543 compounds
    HY-L078 肠道菌群代谢化合物库
    Gut Microbial Metabolite Library
    Compound library containing varieties of metabolites from gut microbiome. 218 compounds
    HY-L058 糖酵解化合物库
    Glycolysis Compound Library
    Compound library containing all kinds of glycolysis compounds. 562 compounds
    HY-L012 代谢/蛋白酶化合物库
    Metabolism/Protease Compound Library
    Compound library targeting metabolic regulation and related diseases. 3526 compounds
  • HY-L097 动物模型诱导剂库
    Animal Disease Model Inducer Library
    Compound library containing all kind of small molecules that used for inducing different kinds of animal disease models. 50 compounds
    HY-L100 肿瘤诱导化合物库
    Tumorigenesis-Related Compound Library
    Compound library containing all kind of small molecules that have been identified with carcinogenic activity either in humans or in animal models. 129 compounds
    HY-L137 分子胶化合物库
    Molecular Glue Compound Library
    Compound library containing various molecular glue compounds. 31 Compounds compounds
    HY-L096 药用辅料化合物库
    Inactive Ingredient Library
    Compound library containing all kind of inactive ingredients that do not increase or affect the therapeutic action of the active ingredient, which is usually the active drug. 195 compounds
    HY-L098 药物代谢物库
    Drug Metabolite Library
    Compound Library containing variety of drug metabolites. 110 compounds
    HY-L076 肝脏毒性化合物库
    Drug-Induced Liver Injury (DILI) Compound Library
    Compound library containing a unique collection of hepatotoxicity causing compounds. 1292 compounds
    HY-L093 食品添加剂库
    Food Additive Library
    Compound library containing different kinds of food additives. 431 compounds
    HY-L094 食物来源化合物库
    Food-Sourced Compound Library
    Compound library containing different kinds of compounds from food. 1831 compounds
    HY-L023 抗体偶联药物毒素分子库
    Toxins for Antibody-Drug Conjugate Research Library
    Compound library containing all kinds of cytotoxins involved in the synthesis of ADC drugs. 45 compounds
    HY-L028 可透过中枢神经系统化合物库
    CNS-Penetrant Compound Library
    Compound library containing molecules that can penetrate the BBB into brain. 757 compounds
    HY-L061 口服活性化合物库
    Orally Active Compound Library
    Compound library containing small molecules with high oral bioavailability. 2842 compounds
    HY-L063 化学探针化合物库
    Chemical Probe Library
    Compound library containing all kinds of chemical probes. 274 compounds
  • HY-L033 拟肽化合物库
    Peptidomimetic Library
    Mimicries of bioactive peptide used for drug discovery. 544 compounds
    HY-L036 共价化合物库
    Covalent Screening Library
    Compound library containing molecules that form a covalent bond with a protein target. 1644 compounds
    HY-L036P 共价化合物库 Plus
    Covalent Screening Library Plus
    Compound library containing compounds that show irreversible covalent binding with target proteins. 3022 compounds
    HY-L041 大环类化合物库
    Macrocyclic Compound Library
    Bioactive compounds containing the macrocyclic structure. 303 compounds
    HY-L138 杂环化合物库
    Heterocyclic Compound Library
    Compound library containing diverse Heterocyclic compounds. 5447 compounds
    HY-L042 糖苷类化合物库
    Glycoside Compound Library
    Bioactive compounds containing the glycoside structure. 687 compounds
    HY-L043 脂类化合物库
    Lipid Compound Library
    Bioactive compounds containing the lipid structure. 1172 compounds
    HY-L044 核苷类化合物库
    Nucleotide Compound Library
    Bioactive compounds containing the nucleotide structure. 332 compounds
    HY-L105 多肽库
    Peptide Library
    A unique collection of amino acid derivatives, blocking peptides, and bioactive peptides. 1416 compounds
    HY-L110 环肽库
    Cyclic Peptide Library
    Compound library containing different kinds of cyclic peptide. 65 compounds
  • HY-L032 片段化合物库
    Fragment Library
    Unique compounds developed for fragment-based drug discovery. 20314 compounds
    HY-L903 3D Diverse Fragment Library
    3D Diverse Fragment Library
    Unique 3D diversity fragment library: a new opportunity for fragment-based drug discovery (FBDD). 5196 compounds
  • HY-L136 凝血-抗凝血化合物库
    Coagulation and Anti-coagulation Compound Library
    Compound library containing a variety of Coagulation and Anti-coagulation related inhibitors and activators. 763 compounds
    HY-L095 机械感受器化合物库
    Mechanoreceptors Compound Library
    Compound library containing all kind of small molecules associated with mechanoreceptors. 203 compounds
    HY-L072 外泌体化合物库
    Exosomes Compound Library
    Compound library containing various kinds of molecules used in the regulation research of exosomes secretion. 39 compounds
    HY-L054 内质网应激化合物库
    Endoplasmic Reticulum Stress Compound Library
    Compound library used for endoplasmic reticulum stress (ER stress) signaling research. 174 compounds
    HY-L089 线粒体靶向化合物库
    Mitochondria-Targeted Compound Library
    Compound library acting on mitochondria and related enzyme. 474 compounds
    HY-L088 血管生成化合物库
    Angiogenesis-Related Compound Library
    Compound library targeting angiogenesis signaling pathways. 1609 compounds
    HY-L060 细胞骨架化合物库
    Cytoskeleton Compound Library
    Compound library containing all kinds of cytoskeletal signaling pathway compounds. 1034 compounds
    HY-L062 神经递质受体化合物库
    Neurotransmitter Receptor Compound Library
    Compound library targeting variety of neurotransmitter receptors. 1449 compounds
    HY-L037 抗氧化化合物库
    Antioxidant Compound Library
    Compound library containing all kinds of small molecules with anti-oxidation activity 1169 compounds
    HY-L038 诱导分化化合物库
    Differentiation Inducing Compound Library
    Compound library used in the regulation research of induced pluripotent stem cells 1179 compounds
    HY-L039 细胞重编程化合物库
    Reprogramming Compound Library
    Compound library used in the regulation research of cell dedifferentiation 1642 compounds
    HY-L050 泛素化化合物库
    Ubiquitination Compound Library
    Compound library targeting the regulation of ubiquitination modification. 210 compounds
    HY-L004 细胞周期/DNA 损伤化合物库
    Cell Cycle/DNA Damage Compound Library
    Compound library targeting the progression of the cell cycle. 1593 compounds
    HY-L005 表观遗传化合物库
    Epigenetics Compound Library
    Compound library targeting epigenetics modification. 976 compounds
    HY-L006 GPCR/G 蛋白化合物库
    GPCR/G Protein Compound Library
    Compound library targeting GPCR-related signaling and diseases. 1876 compounds
    HY-L109 PPI抑制剂库
    Protein-protein Interaction Inhibitor Library
    Compound library containing all kinds of protein-protein interaction inhibitors. 479 compounds
    HY-L024 组蛋白修饰化合物库
    Histone Modification Research Compound Library
    Compound library targeting the regulation of histone modification. 487 compounds
    HY-L007 免疫/炎症化合物库
    Immunology/Inflammation Compound Library
    Compound library with immunological and anti-inflammation activity. 3983 compounds
    HY-L008 JAK/STAT 化合物库
    JAK/STAT Compound Library
    Compound library targeting JAK/STAT signaling. 325 compounds
    HY-L081 磷酸酶抑制剂库
    Phosphatase Inhibitor Library
    Compound library containing all kinds of phosphatase inhibitors. 95 compounds
    HY-L009 激酶抑制剂库
    Kinase Inhibitor Library
    Compound library containing all kinds of kinase inhibitors. 2559 compounds
    HY-L010 MAPK 化合物库
    MAPK Compound Library
    Compound library targeting MAPK/ERK signaling. 334 compounds
    HY-L011 膜转运蛋白/离子通道化合物库
    Membrane Transporter/Ion Channel Compound Library
    Compound library targeting the movement of ions/molecules across membrane. 1132 compounds
    HY-L013 神经信号化合物库
    Neuronal Signaling Compound Library
    Compound library targeting neuronal regulation. 2052 compounds
    HY-L090 转录因子化合物库
    Transcription Factor-Targeted Library
    Compound library containing all kind of small molecular compounds targeting transcription factors. 1023 compounds
    HY-L014 NF-κB 信号化合物库
    NF-κB Signaling Compound Library
    Compound library targeting NF-κB signaling. 646 compounds
    HY-L015 PI3K/Akt/mTOR 化合物库
    PI3K/Akt/mTOR Compound Library
    Compound library targeting PI3K/Akt/mTOR signaling. 468 compounds
    HY-L016 蛋白酪氨酸激酶化合物库
    Protein Tyrosine Kinase Compound Library
    Compound library containing all kinds of protein tyrosine kinase inhibitors. 859 compounds
    HY-L017 干细胞化合物库
    Stem Cell Signaling Compound Library
    Compound library used in the regulation research of all kinds of stem cells. 1397 compounds
    HY-L018 TGF-beta/Smad 化合物库
    TGF-beta/Smad Compound Library
    Compound library targeting TGF-beta/Smad signaling. 168 compounds
    HY-L020 Wnt/Hedgehog/Notch 化合物库
    Wnt/Hedgehog/Notch Compound Library
    Compound library targeting Wnt/Hedgehog/Notch signaling. 277 compounds
    HY-L045 氧感应化合物库
    Oxygen Sensing Compound Library
    Compound library targeting oxygen sensing signaling pathways and related proteins. 1967 compounds
    HY-L117 钙离子通道阻断剂库
    Calcium Channel Blocker Library
    Compound library containing a variety of calcium channel blockers and antagonists. 124 compounds
    HY-L118 钠离子通道阻断剂库
    Sodium Channel Blocker Library
    Compound library containing a variety of sodium channel blockers and antagonists. 109 compounds
    HY-L119 钾离子通道化合物库
    Potassium Channel Compound Library
    Compound library containing a variety of potassium channel inhibitors and activators. 173 compounds
    HY-L120 GABA 受体化合物库
    GABA Receptor Compound Library
    Compound library containing various GABA receptor inhibitors and activators. 108 compounds
    HY-L121 5-羟色胺受体化合物库
    5-HT Receptor Compound Library
    Compound library containing 5-HT receptor inhibitors and activators. 244 compounds
    HY-L128 E3泛素连接酶配体库
    E3 Ligase Ligand Library
    Compound library containing several ligands for E3 ligase. 44 compounds
    HY-L129 靶蛋白配体库
    Target Protein Ligand Library
    Compound library containing several ligands for target proteins of PROTAC. 30 compounds
    HY-L126 核受体化合物库
    Nuclear Receptor Compound Library
    Compound library containing a variety of nuclear receptor inhibitors and activators. 550 compounds
    HY-L132 趋化因子化合物库
    Chemokine Compound Library
    Compound library containing a variety of Chemokine or Chemokine receptor inhibitors and activators. 127 compounds
    HY-L131 成骨化合物库
    Osteogenesis Compound Library
    Compound library containing all kinds of involved in bone formation compounds. 356 compounds