1. 重组蛋白
  2. Receptor Proteins
  3. G-Protein-Coupled Receptors (GPCRs)

G-Protein-Coupled Receptors (GPCRs)  (G-蛋白偶联受体)

G 蛋白偶联受体 (GPCRs),也称7TM受体,是最大和最重要的一类整合膜蛋白家族的统称。它们介导细胞对大多数激素、代谢物、细胞因子和神经递质的反应,因此是药物发现的“富有成效靶点”。GPCRs 能够感知胞外信号并将其转化为异源三聚体 G蛋白,再由异源三聚体G蛋白将这些信号转导到胞内合适的下游效应体,从而在各个信号通路中发挥重要作用。 GPCRs根据序列和功能分为6类:视紫红质 (A 类)、分泌素 (B 类)、代谢性谷氨酸受体 (C类)、真菌交配信息素受体 (D类)、cAMP 受体 (E类) 和 frizzled/smoothened 受体 (F类)。根据脊椎动物中的替代分类系统 (GRAFS),GPCRs 可分为视紫红质 (A 类)、分泌素(B 类)、谷氨酸 (C 类)、粘附和Frizzled/Taste2 受体。

目录号 产品名 / 同用名 种属 表达系统
  • HY-P75370
    CD97 Protein, Human (HEK293, hFc)

    Adhesion G protein-coupled receptor E5; CD97; ADGRE5

    Human HEK293
  • HY-P70352
    GLP1R Protein, Human (HEK293, Fc)

    rHuGlucagon-like peptide 1 receptor/GLP1R, Fc; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R

    Human HEK293
  • HY-P72674
    CXCR4 Protein, Human (HEK293, Fc)

    C-X-C chemokine receptor type 4; CXC-R4; LESTR; LAP-3; NPYRL; CD184; SDF-1 receptor

    Human HEK293
  • HY-P70210
    Frizzled-1 Protein, Mouse (HEK293, Fc)

    rMuFrizzled-1/Fz-1, Fc; Frizzled-1; Fz-1; mFz1; Fzd1; Frizzled homolog 1

    Mouse HEK293
  • HY-P70918
    FZD2 Protein, Mouse (HEK293, Fc)

    Frizzled-2; Fz-2; mFz2; Fzd2; frizzled (Drosophila) homolog 2

    Mouse HEK293
  • HY-P74140
    Frizzled-4/CD344 Protein, Human (HEK293, His)

    CD344 antigen; CD344; EVR1; FEVR; Frizzled-4; Fz-4; FZD4

    Human HEK293
  • HY-P74141
    Frizzled-4/CD344 Protein, Human (HEK293, Fc)

    CD344 antigen; CD344; EVR1; FEVR; Frizzled-4; Fz-4; FZD4

    Human HEK293
  • HY-P77589
    CCR2b Protein-VLP, Human (HEK293)

    C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2

    Human HEK293
  • HY-P77590
    CCR2b Protein-VLP, Human (Biotinylated, HEK293)

    C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2

    Human HEK293
  • HY-P77958
    GPRC5D Protein-VLP, Human (HEK293)

    GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor

    Human HEK293
  • HY-P77959
    GPRC5D Protein-VLP, Human (Biotinylated, HEK293)

    GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor

    Human HEK293
  • HY-P72198
    FSHR Protein, Human (His)

    Follicle stimulating hormone receptor; Follicle stimulating hormone receptor isoform 1; Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; Fshr; FSHR_HUMAN; FSHRO; LGR1; MGC141667; MGC141668; ODG1; ovarian dysgenesis 1

    Human E. coli
  • HY-P70915
    Frizzled-8 Protein, Human (HEK293, His)

    frizzled 8; frizzled family receptor 8; Frizzled8; Frizzled-8; FZ-8; FZD8; hFZ8

    Human HEK293
  • HY-P71730
    EDNRA Protein, Human (P.pastoris, His)

    Ednra; ET A; ET-A; ETA; ETA R; ETA-R; ETAR; ETRA; G protein coupled receptor; hET AR; hET-AR; MFDA

    Human P. pastoris
  • HY-P72138
    CHRM1 Protein, Rat (His)

    Chrm1; Chrm-1Muscarinic acetylcholine receptor M1

    Rat E. coli
  • HY-P72159
    CXCR4 Protein, Human (His-SUMO)

    C-X-C chemokine receptor type 4; CD184; CD184 antigen; Chemokine C X C motif; receptor 4; Chemokine CXC Motif Receptor 4; CXC-R4; CXCR-4; CXCR4; CXCR4_HUMAN; D2S201E; FB22; Fusin; HM89; HSY3RR; LAP 3; LAP3; LCR1; LESTR; Leukocyte derived seven transmembrane domain receptor; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide associated protein 3; Neuropeptide Y receptor Y3; NPY3R; NPYR; NPYRL; NPYY3; NPYY3R; Probable G protein coupled receptor lcr1 homolog; SDF 1 receptor; SDF-1 receptor; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR; Stromal cell derived factor 1 receptor; Stromal cell-derived factor 1 receptor; WHIM; WHIMS

    Human E. coli
  • HY-P72160
    CXCR4 Protein, Human (GST)

    C-X-C chemokine receptor type 4; CD184; CD184 antigen; Chemokine C X C motif; receptor 4; Chemokine CXC Motif Receptor 4; CXC-R4; CXCR-4; CXCR4; CXCR4_HUMAN; D2S201E; FB22; Fusin; HM89; HSY3RR; LAP 3; LAP3; LCR1; LESTR; Leukocyte derived seven transmembrane domain receptor; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide associated protein 3; Neuropeptide Y receptor Y3; NPY3R; NPYR; NPYRL; NPYY3; NPYY3R; Probable G protein coupled receptor lcr1 homolog; SDF 1 receptor; SDF-1 receptor; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR; Stromal cell derived factor 1 receptor; Stromal cell-derived factor 1 receptor; WHIM; WHIMS

    Human E. coli
  • HY-P72206
    GLP1R Protein, Mouse (His-SUMO)

    Glp1r; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R

    Mouse E. coli
  • HY-P72372
    Frizzled-8 Protein, Human (Biotinylated, HEK293, His-Avi)

    frizzled family receptor 8; Frizzled8; Frizzled-8; FZ-8; FZD8; hFZ8

    Human HEK293
  • HY-P74134
    Frizzled-6 Protein, Human (HEK293, His)

    Frizzled homolog 6 (Drosophila); Frizzled-6; fz-6; FZD6

    Human HEK293
目录号 产品名 作用方式 纯度