1. Signaling Pathways
  2. PROTAC
  3. LYTACs

LYTACs (溶酶体靶向嵌合体)

Lysosome targeting chimera (LYTAC) degrades target proteins via lysosomal pathway rather than common proteasome pathway. LYTAC degrades target proteins by binding to asialoglycoprotein receptor on lysosomal through its asialoglycoprotein receptor ligand. Another side of LYTAC is usually an antibody so it can bind to target protein for degradation.

LYTACs 相关产品 (4):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-139482
    tri-GalNAc-COOH 1953146-81-0 ≥99.0%
    tri-GalNAc-COOH 是一种去唾液酸糖蛋白受体 (ASGPR) 配体,可用于溶酶体靶向嵌合体 (LYTAC) 研究。
    tri-GalNAc-COOH
  • HY-145013
    tri-GalNAc-COOH (acetylation)
    tri-GalNAc-COOH acetylation 是 tri-GalNAc-COOH 的乙酰化和修饰形式。tri-GalNAc-COOH acetylation 可用于合成LYTAC。
    tri-GalNAc-COOH (acetylation)
  • HY-142881
    D-MoDE-A (1) 2378837-67-1
    D-MoDE-A (1)是一种双功能小分子,通过去唾液酸糖蛋白受体(ASGPR)介导细胞外蛋白的降解。
    D-MoDE-A (1)
  • HY-142885
    M-MoDE-A (2) 2378837-56-8
    M-MoDE-A (2) 是一种双功能小分子,通过去唾液酸糖蛋白受体(ASGPR)介导细胞外蛋白的降解。
    M-MoDE-A (2)
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