1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Procollagen C Proteinase

Procollagen C Proteinase (前胶原C端蛋白酶)

Procollagen C proteinase (PCP) and its enhancer protein (PCPE) are key to collagen fibril-assembly and extracellular matrix formation. PCP cleaves the carboxyl-propeptides of procollagens types I, II, and III and this initiates the self-assembly of collagen fibrils. PCP can also process pro-lysyl oxidase and laminin 5, and it may cleave the type V procollagen N-propeptides. Procollagen processing by PCP is stimulated by PCPE, a glycoprotein that binds to the C-propeptide of type I procollagen through its N-terminal CUB domains. PCP/BMP-1 related proteases can activate TGF-β-like growth factors. PCPs have important biological functions in addition to their role in collagen fibril assembly.

Procollagen C Proteinase 相关产品 (1):

目录号 产品名 作用方式 纯度
  • HY-13102
    UK-383367 Inhibitor ≥99.0%
    UK-383367 (UK 383367) 是一种有效、选择性的 BMP-1 抑制剂,IC50 值为 44 nM;对其选择性远高于 MMP 1,2,3,9 和 14。
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