2. Signaling Pathways
  3. Cytoskeleton
  4. Connexin

Connexin (连接蛋白)

Connexins (Cx) are members of a protein family that forms intercellular channels localised in gap junction (GJ) plaques and single transmembrane channels called hemichannels. They participate in intercellular communication or communication between the intracellular and extracellular environments. Connexins affect cell homeostasis, growth and differentiation by enabling the exchange of metabolites or by interfering with various signalling pathways.

Connexin 相关产品 (2):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-149318
    VRT-534 Inhibitor 98.32%
    VRT-534 (Compound 3) 是一种靶向连接蛋白 26 (Cx26) 的化学伴侣。Vrt-534 与重组 WT Cx26 和突变体 Cx26 K188N 呈现剂量效应结合，其 EC50 分别为 19 μM 和 5 μM。Vrt-534 可用于听力障碍相关研究。
    VRT-534
  • HY-149318B
    (R,R)-VRT-534 Inhibitor
    (R,R)-VRT-534 是 VRT-534 (HY-149318) 的 (R,R)-对映异构体。VRT-534 (Compound 3) 是一种靶向连接蛋白 26 (Cx26) 的化学伴侣。Vrt-534 与重组 WT Cx26 和突变体 Cx26 K188N 呈现剂量效应结合，其 EC50 分别为 19 μM 和 5 μM。Vrt-534 可用于听力障碍相关研究。
    (R,R)-VRT-534
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