1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Steroid Sulfatase

Steroid Sulfatase (甾体硫酸酯酶)

Steroid Sulfatase

甾体硫酸酯酶 (STS) 是一种糖基化蛋白,表观分子量约为 63–73 kDa。STS 催化 3-羟基类固醇硫酸酯的水解,这些硫酸酯是活性 3-羟基类固醇的无活性转运或前体形式。STS 可以裂解雌酮硫酸酯 (E1S) 和脱氢表雄酮硫酸酯 (DHEAS)。STS 是治疗激素依赖性疾病的潜在靶点。

Steroid sulfatase (STS) is a glycosylated protein with an apparent molecular weight of about 63–73 kDa. STS catalyzes the hydrolysis of the sulfate esters of 3-hydroxy steroids, which are inactive transport or precursor forms of the active 3-hydroxy steroids. STS can cleave estrone sulfate (E1S) and DHEA sulfate (DHEAS). STS is a potential target for the treatment of hormone-dependent diseases[1].

Steroid Sulfatase 相关产品 (21):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-123420
    Dinordrin
    Dinordrin (Dinordrin I) 是一种具有黄体溶解作用的类固醇。Dinordrin 可导致血浆雌激素和孕酮水平下降。
    Dinordrin