1. Neuronal Signaling
    Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. BDNF(human)

BDNF(human) 

目录号: HY-P1177
产品使用指南

BDNF (human) 是中枢神经系统中的一种神经营养物质 (neurotrophin),介导神经元的存活和分化。BDNF (human) 与 TrkB 结合,导致受体胞内区域酪氨酸残基二聚和自磷酸化。BDNF 可用于神经退行性和精神疾病的研究。

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Custom Peptide Synthesis

BDNF(human) Chemical Structure

BDNF(human) Chemical Structure

CAS No. : 218441-99-7

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Description

BDNF (human) is a neurotrophin in the central nervous system and mediates survival and differentiation of neurons. BDNF (human) binds to TrkB and leads to the dimerization and autophosphorylation of tyrosine residues in the intracellular domain of the receptor. BDNF (human) can be used for study of neurodegenerative and psychiatric disorder[1][2].

IC50 & Target

IC50: TrkB[1]

Molecular Weight

13526.35

Formula

C₅₈₁H₉₄₁N₁₇₇O₁₇₇S₉

CAS No.

218441-99-7

Sequence Shortening

HSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYNRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

BDNF(human)Trk ReceptorTropomyosin related kinase receptorNeurotrophinpsychiatricdisorderneurodegenerativeInhibitorinhibitorinhibit

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产品名称:
BDNF(human)
目录号:
HY-P1177
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