1. Biology Dictionary
  2. DNA polymerase

DNA polymeraseDNA 聚合酶

释义:

DNA polymerases are essential enzymes responsible for replication and repair of DNA in all organisms. Based on sequence homology, DNA polymerases have distinct families, including A, B, X, and Y. To replicate DNA with high fidelity, DNA polymerases must select the correct incoming nucleotide substrate during each cycle of nucleotide incorporation, in accordance with the templating base. When an incorrect nucleotide is sometimes inserted, the polymerase uses a separate 3'→5' exonuclease to remove the misincorporated base (proofreading).

DNA 聚合酶是负责所有生物体中 DNA 复制和修复的必需酶。 基于序列同源性,DNA 聚合酶具有不同的家族,包括 A、B、X 和 Y。为了以高保真度复制 DNA,DNA 聚合酶必须根据模板碱基在核苷酸掺入的每个循环中选择正确的传入核苷酸底物 . 当有时插入不正确的核苷酸时,聚合酶使用单独的 3'→5' 核酸外切酶去除错误掺入的碱基(校对)。

MCE 生物医学词典

MCE 生物医学词典是全面和专业的生物学术专有名词和主题数据合集。在这里您可以搜索到您想了解的专业名词的准确解释,并且所有名词解释均有权威书籍或者高影响因子文献的支持。
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #