1. Biology Dictionary
  2. Leukemia inhibitory factor (LIF)

Leukemia inhibitory factor (LIF)白血病抑制因子

释义:

Leukemia inhibitory factor (LIF) is a multi-functional cytokine of the interleukin-6 (IL-6) superfamily. LIF Initially identified as a factor that inhibits the proliferation of murine myeloid leukemia cells, LIF displays important functions in many physiological and pathological processes, including regulating cell proliferation, pluripotent stem cell self-renewal, tissue/organ development and regeneration, neurogenesis and neural regeneration, maternal reproduction, inflammation, infection, immune response, and metabolism.

白血病抑制因子 (LIF) 是白细胞介素 6 (IL-6) 超家族的多功能细胞因子。LIF 最初被确定为抑制小鼠髓系白血病细胞增殖的因子,LIF 在许多生理和病理过程中发挥重要作用,包括调节细胞增殖、多能干细胞自我更新、组织/器官发育和再生、神经发生和神经再生 、母体生殖、炎症、感染、免疫反应和新陈代谢。

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