1. Biology Dictionary
  2. Post-translational modifications (PTMs)

Post-translational modifications (PTMs)翻译后修饰

释义:

Post-translational modifications (PTMs) are an essential regulator of non-functional protein aggregation in the pathogenesis of Neurodegenerative diseases (NDDs). Any alteration in the post-translational mechanism and the protein quality control system, for instance, molecular chaperone, ubiquitin-proteasome system, autophagy-lysosomal degradation pathway, enhances the accumulation of misfolded protein, which causes neuronal dysfunction.

翻译后修饰 (PTM) 是神经退行性疾病 神经退行性疾病 发病机制中非功能性蛋白质聚集的重要调节因子。翻译后机制和蛋白质质量控制系统的任何改变,例如分子伴侣、泛素-蛋白酶体系统、自噬-溶酶体降解途径,都会增加错误折叠蛋白质的积累,从而导致神经元功能障碍。

MCE 生物医学词典

MCE 生物医学词典是全面和专业的生物学术专有名词和主题数据合集。在这里您可以搜索到您想了解的专业名词的准确解释,并且所有名词解释均有权威书籍或者高影响因子文献的支持。
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #