1. Gene
  2. Apela - apelin receptor early endogenous ligand Gene

Apela - apelin receptor early endogenous ligand Gene

种属: Mus musculus

同用名: Ela; Ende; Elabela; Gm10664

基因 ID: 100038489 | 基因类型: protein coding

关于 Apela

功能概要

Predicted to enable apelin receptor binding activity and hormone activity. Involved in circulatory system development and positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. Acts upstream of or within SMAD protein signal transduction. Located in extracellular space. Is expressed in several structures, including embryo ectoderm; embryo endoderm; gut; heart; and metanephros. Used to study pre-eclampsia. Orthologous to human APELA (apelin receptor early endogenous ligand). [provided by Alliance of Genome Resources, Apr 2022]

Apela 基因产物(2)

mRNA Protein Name
NM_001297554.2 NP_001284483.1 apelin receptor early endogenous ligand precursor
NM_001399422.1 NP_001386351.1 apelin receptor early endogenous ligand precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in coronary vasculature development IMP
IMP: 通过突变表型推断
28890073 MGI
involved in embryonic heart tube development IMP
IMP: 通过突变表型推断
28663440 MGI
involved in placenta blood vessel development IMP
IMP: 通过突变表型推断
28663440 MGI
involved in positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis IMP
IMP: 通过突变表型推断
28890073 MGI
acts upstream of or within regulation of blood pressure IMP
IMP: 通过突变表型推断
32829380 MGI
involved in vasculogenesis IMP
IMP: 通过突变表型推断
28663440 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
28663440 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

apelin receptor early endogenous ligand

Protein Elabela

protein Toddler

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Apela NCBI NCBI:100506013