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  2. MRLN - myoregulin Gene

MRLN - myoregulin Gene

中文名称:肌调节蛋白

种属: Homo sapiens

同用名: M1; MLN; MUSER1; Linc-RAM; LINC00948

基因 ID: 100507027 | 基因类型: protein coding

关于 MRLN

Cytogenetic location: 10q21.2 Genomic coordinates (GRCh38): 10:59,736,692-59,753,455 (from NCBI)

This gene has 11 transcripts (splice variants) and 22 orthologues. Biased expression in kidney (RPKM 2.5), prostate (RPKM 1.2) and 3 other tissues.

功能概要

该基因编码的小肽与小肽肌脂蛋白和受磷蛋白具有结构相似性,后者是肌浆网 CA (2+) -ATP 酶 (SERCA) 的关键调节剂。这种蛋白质被认为具有与这些肽相似的功能,通过抑制 SERCA 的 CA (2+) 泵活性来调节肌浆网中的 CA (2+) 再摄取。可变剪接导致多个转录本变体。[RefSeq 提供,2015 年 6 月]

This gene encodes a small peptide that shares structural similarity to the small peptides sarcolipin and phospholamban, which are key regulators of sarcoplasmic reticulum CA(2+)-ATPases (SERCAs). This protein is thought to have a similar function to these peptides, regulating CA(2+) reuptake in the sarcoplasmic reticulum by inhibiting the CA(2+) pump activity of SERCAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2015]

MRLN 基因产物(2)

mRNA Protein Name
NM_001304731.2 NP_001291660.1 myoregulin
NM_001304732.2 NP_001291661.1 myoregulin
蛋白主名 其他名称

myoregulin

Linc-RNA activator of myogenesis

直系同源

种属 基因名 来源 基因 ID
Mus musculus MRLN MGD MGI:1916813
Rattus norvegicus MRLN RGD RGD:6490783