1. Gene
  2. Acacb - acetyl-Coenzyme A carboxylase beta Gene

Acacb - acetyl-Coenzyme A carboxylase beta Gene

种属: Mus musculus

同用名: Acc2; Accb

基因 ID: 100705 | 基因类型: protein coding

关于 Acacb

功能概要

Enables Acetyl-CoA Carboxylase activity. Involved in several processes, including energy homeostasis; malonyl-CoA biosynthetic process; and negative regulation of fatty acid beta-oxidation. Acts upstream of or within fatty acid biosynthetic process. Located in mitochondrion. Is expressed in axial skeleton; cranium; and liver. Orthologous to human ACACB (Acetyl-CoA Carboxylase beta). [provided by Alliance of Genome Resources, Apr 2022]

Acacb 基因产物(4)

mRNA Protein Name
NM_001403527.1 NP_001390456.1 acetyl-CoA carboxylase 2 isoform 1 precursor
NM_001403528.1 NP_001390457.1 acetyl-CoA carboxylase 2 isoform 3
NM_001403529.1 NP_001390458.1 acetyl-CoA carboxylase 2 isoform 4
NM_133904.3 NP_598665.2 acetyl-CoA carboxylase 2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables acetyl-CoA carboxylase activity IDA
IDA: 通过直接分析推断
17210641 MGI
enables acetyl-CoA carboxylase activity IMP
IMP: 通过突变表型推断
17210641 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in energy homeostasis IMP
IMP: 通过突变表型推断
12920182 MGI
acts upstream of or within fatty acid biosynthetic process IMP
IMP: 通过突变表型推断
17210641 MGI
involved in malonyl-CoA biosynthetic process IMP
IMP: 通过突变表型推断
18487439 MGI
involved in negative regulation of fatty acid beta-oxidation IMP
IMP: 通过突变表型推断
12920182 MGI
involved in negative regulation of fatty acid oxidation IMP
IMP: 通过突变表型推断
11283375 MGI
involved in negative regulation of lipid catabolic process IMP
IMP: 通过突变表型推断
15677334 MGI
involved in positive regulation of heart growth IMP
IMP: 通过突变表型推断
18487439 MGI
involved in positive regulation of lipid storage IMP
IMP: 通过突变表型推断
11283375 MGI
involved in regulation of glucose metabolic process IMP
IMP: 通过突变表型推断
15677334 MGI
involved in response to nutrient levels IMP
IMP: 通过突变表型推断
12920182 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
10677481 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

acetyl-CoA carboxylase 2

ACC-beta

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acacb NCBI NCBI:32