SNUPN - snurportin 1 Gene

中文名称：营养素 1

种属: Homo sapiens

同用名: KPNBL; RNUT1; Snurportin1

关于 SNUPN

功能概要

剪接体 snRNPs U1、U2、U4 和 U5 的核输入取决于复杂核定位信号的存在。后者由 U snRNA 的 5'-2,2,7-末端三甲基鸟苷 (m3G) 帽结构和 Sm 核心结构域组成。由该基因编码的蛋白质与 m3G-cap 特异性相互作用，并作为 snRNP 特异性核输入受体发挥作用。已经为该基因鉴定了编码相同蛋白质的可变剪接转录物变体。[RefSeq 提供，2008 年 7 月]

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]