2. Gene
  3. UST - uronyl 2-sulfotransferase Gene

UST - uronyl 2-sulfotransferase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：糖醛酸 2-磺基转移酶

种属: Homo sapiens

同用名: 2OST

基因 ID: 10090 | 基因类型: protein coding

关于 UST

Cytogenetic location: 6q25.1 Genomic coordinates (GRCh38): 6:148,747,030-149,076,990 (from NCBI)

This gene has 3 transcripts (splice variants), 218 orthologues and 1 paralogue. Broad expression in thyroid (RPKM 10.7), adrenal (RPKM 4.5) and 21 other tissues.

功能概要

糖醛酰 2-磺基转移酶将硫酸盐转移到糖醛酸残基的 2 位，例如硫酸皮肤素中的艾杜糖醛残基和硫酸软骨素中的葡萄糖醛酸残基 (Kobayashi 等人，1999 [PubMed 10187838]) 。[OMIM 提供，2008 年 3 月]

Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008]

UST 基因产物(1)

mRNA Protein Name
NM_005715.3 NP_005706.1 uronyl 2-sulfotransferase

UST 蛋白结构

Sulfotransfer_2

Sulfotransfer_2: Sulfotransferase family (104 - 356)

  • 0
  • 100
  • 200
  • 300
  • 406 a.a.
蛋白主名 其他名称

uronyl 2-sulfotransferase

dermatan/chondroitin sulfate 2-sulfotransferase

关联疾病

疾病名称 别名
Breast Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma

Pericanalicular Fibroadenoma Of Breast
Acute Retinal Necrosis Syndrome

Acute Retinal Necrosis

Retinal Necrosis Syndrome, Acute
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15573 UST Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18334 Ust Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24813 Ust Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus UST RGD RGD:1304743
Macaca mulatta UST VGNC VGNC:79067
Bos taurus UST VGNC VGNC:107018
Felis catus UST VGNC VGNC:66900
Mus musculus UST MGD MGI:2442406
Canis familiaris UST VGNC VGNC:48207
Others UST NCBI
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