2. Gene
  3. ADGRG2 - adhesion G protein-coupled receptor G2 Gene

ADGRG2 - adhesion G protein-coupled receptor G2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：粘附 G 蛋白偶联受体 G2

种属: Homo sapiens

同用名: HE6; EDDM6; GPR64; CBAVDX; TM7LN2

基因 ID: 10149 | 基因类型: protein coding

关于 ADGRG2

Cytogenetic location: Xp22.13 Genomic coordinates (GRCh38): X:18,989,307-19,122,956 (from NCBI)

This gene has 11 transcripts (splice variants), 219 orthologues, 42 paralogues and is associated with 2 phenotypes. Biased expression in stomach (RPKM 3.6), lymph node (RPKM 2.3) and 13 other tissues.

功能概要

该基因编码 G 蛋白偶联受体家族的一个成员，该家族被描述为附睾特异性跨膜蛋白。编码的蛋白质可能经过蛋白水解处理，因为它包含一个基序，在该家族的某些成员中显示为蛋白质断裂基序 (PMID: 11973329) 。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2011 年 8 月]

This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

ADGRG2 基因产物(9)

mRNA Protein Name
NM_001079858.3 NP_001073327.1 adhesion G-protein coupled receptor G2 isoform 1 precursor
NM_001079859.3 NP_001073328.1 adhesion G-protein coupled receptor G2 isoform 2 precursor
NM_001079860.3 NP_001073329.1 adhesion G-protein coupled receptor G2 isoform 3 precursor
NM_001184833.2 NP_001171762.1 adhesion G-protein coupled receptor G2 isoform 5 precursor
NM_001184834.2 NP_001171763.1 adhesion G-protein coupled receptor G2 isoform 6 precursor
NM_001184835.2 NP_001171764.1 adhesion G-protein coupled receptor G2 isoform 7 precursor
NM_001184836.2 NP_001171765.1 adhesion G-protein coupled receptor G2 isoform 8 precursor
NM_001184837.2 NP_001171766.1 adhesion G-protein coupled receptor G2 isoform 9 precursor
NM_005756.4 NP_005747.2 adhesion G-protein coupled receptor G2 isoform 4 precursor

ADGRG2 蛋白结构

GPS

GPS: GPCR proteolysis site, GPS, motif (568 - 612)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (626 - 875)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1017 a.a.
蛋白主名 其他名称

adhesion G-protein coupled receptor G2

G protein-coupled receptor 64

关联疾病

疾病名称 别名
Vas Deferens, Congenital Bilateral Aplasia Of, X-Linked

CBAVDX

Congenital Bilateral Absence Of Vas Deferens, X-Linked

X-Linked Congenital Bilateral Absence Of Vas Deferens

Congenital Bilateral Aplasia Of The Vas Deferens, X-Linked

Male Urogenital Diseases
Vas Deferens, Congenital Bilateral Aplasia Of

Congenital Bilateral Absence Of Vas Deferens

CBAVD

Cavd

Congenital Bilateral Aplasia Of Vas Deferens

Congenital Bilateral Absence Of The Vas Deferens

Congenital Bilateral Agenesis Of Vas Deferens

Absence Of Vas Deferens

Absent Vasa

Congenital Absence Of Vas Deferens

Congenital Aplasia Of Vas Deferens

Absent Vas Deferens

Vas Deferens, Congenital Bilateral Absence
Infertility
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10365 VPM-p15 Agonist 98.18% 否
HY-RS00355 ADGRG2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ADGRG2 VGNC VGNC:37644
Rattus norvegicus ADGRG2 RGD RGD:628618
Bos taurus ADGRG2 VGNC VGNC:25666
Macaca mulatta ADGRG2 VGNC VGNC:69802
Mus musculus ADGRG2 MGD MGI:2446854
Felis catus ADGRG2 VGNC VGNC:67436
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z