1. Gene
  2. ADAMTS13 - Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 Gene

ADAMTS13 - Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 Gene

种属: Rattus norvegicus

基因 ID: 102554393 | 基因类型: protein coding

关于 ADAMTS13

功能概要

Enables endopeptidase activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and response to potassium ion. Located in extracellular space. Biomarker of cholestasis and non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in thrombotic thrombocytopenic purpura. Orthologous to human ADAMTS13 (ADAM metallopeptidase with thrombospondin type 1 motif 13). [provided by Alliance of Genome Resources, Apr 2022]

ADAMTS13 基因产物(12)

mRNA Protein Name
XM_039106138.1 XP_038962066.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X7
XM_039106136.1 XP_038962064.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X5
XM_039106131.1 XP_038962059.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X2
XM_039106140.1 XP_038962068.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X9
XM_039106137.1 XP_038962065.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X6
XM_006233879.3 XP_006233941.3 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X1
XM_039106132.1 XP_038962060.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X3
XM_039106134.1 XP_038962062.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X4
XM_039106133.1 XP_038962061.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X4
XM_039106135.1 XP_038962063.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X4
XM_039106139.1 XP_038962067.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X8
XM_039106141.1 XP_038962069.1 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X10
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables endopeptidase activity IDA
IDA: 通过直接分析推断
19652891 RGD
enables peptidase activity IDA
IDA: 通过直接分析推断
16689760 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-4 IEP
IEP: 通过表达模式推断
18433458 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
22871409 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
18433458 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
18433458 RGD
involved in protein catabolic process IDA
IDA: 通过直接分析推断
19652891 RGD
involved in response to amine IEP
IEP: 通过表达模式推断
17383642 RGD
involved in response to interleukin-4 IEP
IEP: 通过表达模式推断
18433458 RGD
involved in response to potassium ion IEP
IEP: 通过表达模式推断
17804457 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
16689760 RGD
involved in response to tumor necrosis factor IEP
IEP: 通过表达模式推断
18433458 RGD
involved in response to type II interferon IEP
IEP: 通过表达模式推断
18433458 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19652891 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

A disintegrin and metalloproteinase with thrombospondin motifs 13

A disintegrin and metalloproteinase with thrombospondin motifs 13-like

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 mot

直系同源

种属 基因名 来源 基因 ID
Homo sapiens ADAMTS13 NCBI NCBI:11093