2. Gene
  3. PRSS16 - serine protease 16 Gene

PRSS16 - serine protease 16 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：丝氨酸蛋白酶 16

种属: Homo sapiens

同用名: TSSP

基因 ID: 10279 | 基因类型: protein coding

关于 PRSS16

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:27,247,701-27,256,620 (from NCBI)

This gene has 20 transcripts (splice variants), 206 orthologues and 2 paralogues. Broad expression in thyroid (RPKM 6.8), stomach (RPKM 3.4) and 17 other tissues.

功能概要

该基因编码一种仅在胸腺中表达的丝氨酸蛋白酶。它被认为在 T 细胞阳性选择过程中皮质胸腺上皮细胞使用的替代抗原呈递途径中发挥作用。该基因位于 6 号染色体上的大组蛋白基因簇中，靠近主要组织相容性复合体 (MHC) I 类区域。已经描述了第二个转录本变体，但尚未确定其全长性质。[RefSeq 提供，2008 年 7 月]

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]

PRSS16 基因产物(1)

mRNA Protein Name
NM_005865.4 NP_005856.1 thymus-specific serine protease

PRSS16 蛋白结构

Peptidase_S28

Peptidase_S28: Serine carboxypeptidase S28 (64 - 494)

  • 0
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  • 400
  • 514 a.a.
蛋白主名 其他名称

thymus-specific serine protease

protease, serine 16

关联疾病

疾病名称 别名
Capillariasis

Capillaria Infection

Enoplida Infections

Capillariasis Nos

Capillariosis
Pulmonary Embolism And Infarction
Sparganosis

Infection By Sparganum

Larval Diphyllobothriasis

Spirometrosis

Infection By Spirometra Larvae

Larval Dibothriocephaliasis

Sparganosis - Larval Diphyllobothriasis

Spirometriosis

Larval Dibothriocephalus Infestation

Larval Diphyllobothrium Infestation

Larval Dibothriocephalus

Infection Due To Sparganum

Larval Fish Tapeworm Infection

Spirometra Larvae Infestation

Sparganum Infestation

Larval Bothriocephalus Infestation
T-Cell Immunodeficiency With Thymic Aplasia

Nezelof Syndrome

T-Lymphocyte Deficiency

TIDTA

Immune Defect Due To Absence Of Thymus

Thymic Aplasia

Nezelof'S Syndrome

Thymic Dysplasia With Normal Immunoglobulins

Thymic Aplasia Syndrome

T-Lymphocyte Immunodeficiency
Thymic Dysplasia
Paragonimiasis

Infection By Paragonimus

Lung Fluke Disease

Lung Fluke Infection

Pulmonary Paragonimiasis

Paragonimus Westermani Infection

Pulmonary Distomiasis

Parasitic Haemoptysis

Oriental Lung Fluke Disease

Endemic Haemoptysis

Paragonimosis

Pulmonary Distomatosis

Lung Fluke Disorder

Infestation By Paragonimus

Infection Due To Paragonimus Species

Infestation Due To Paragonimus Species

Oriental Lung Fluke Infestation

Endemic Oriental Haemoptysis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11247 PRSS16 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PRSS16 MGD MGI:1859181
Bos taurus PRSS16 VGNC VGNC:33414
Canis familiaris PRSS16 VGNC VGNC:45063
Rattus norvegicus PRSS16 RGD RGD:1306652
Felis catus PRSS16 VGNC VGNC:69090
Macaca mulatta PRSS16 VGNC VGNC:82214
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