1. Gene
  2. ABCA10 - ATP binding cassette subfamily A member 10 Gene

ABCA10 - ATP binding cassette subfamily A member 10 Gene

中文名称:ATP 结合盒亚家族 A 成员 10

种属: Homo sapiens

同用名: EST698739

基因 ID: 10349 | 基因类型: protein coding

关于 ABCA10

Cytogenetic location: 17q24.3 Genomic coordinates (GRCh38): 17:69,148,007-69,244,848 (from NCBI)

This gene has 13 transcripts (splice variants), 133 orthologues and 11 paralogues. Broad expression in ovary (RPKM 9.1), fat (RPKM 3.8) and 18 other tissues.

功能概要

由该基因编码的膜相关蛋白是 ATP 结合盒 (ABC) 转运蛋白超家族的成员。 ABC 蛋白可跨细胞外膜和细胞内膜转运各种分子。 ABC 基因分为七个不同的亚家族 (ABC1、MDR/TAP、MRP、ALD、OABP、GCN20 和 White) 。这种编码的蛋白质是 ABC1 亚家族的成员。 ABC1 亚科的成员包括仅在多细胞真核生物中发现的唯一主要 ABC 亚科。该基因聚集在 17q24 上的其他 4 个 ABC1 家族成员中,但该基因的底物和功能均未知。[RefSeq 提供,2008 年 7 月]

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 Other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008]

ABCA10 基因产物(2)

mRNA Protein Name
NM_001377321.1 NP_001364250.1 ATP-binding cassette sub-family A member 10
NM_080282.4 NP_525021.3 ATP-binding cassette sub-family A member 10

ABCA10 蛋白结构

ABC2_membrane_3

ABC2_membrane_3: ABC-2 family transporter protein (20 - 329)

ABC_tran

ABC_tran: ABC transporter (410 - 556)

ABC2_membrane_3

ABC2_membrane_3: ABC-2 family transporter protein (935 - 1131)

ABC_tran

ABC_tran: ABC transporter (1223 - 1367)

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  • 1543 a.a.
蛋白主名 其他名称

ATP-binding cassette sub-family A member 10

ATP-binding cassette A10