2. Gene
  3. Fbxw11 - F-box and WD-40 domain protein 11 Gene

Fbxw11 - F-box and WD-40 domain protein 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HOS; BTRC2; BTRCP2; Fbxw1b; 2310065A07Rik

基因 ID: 103583 | 基因类型: protein coding

关于 Fbxw11

功能概要

Enables ubiquitin-protein transferase activity. Contributes to ubiquitin protein Ligase activity. Involved in several processes, including cellular protein metabolic process; negative regulation of NIK/NF-kappaB signaling; and positive regulation of circadian rhythm. Located in cytosol and nucleus. Part of SCF ubiquitin Ligase complex. Is expressed in cap mesenchyme; early tubule; ovary; and testis. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]

Fbxw11 基因产物(14)

mRNA Protein Name
NM_001271347.2 NP_001258276.1 F-box/WD repeat-containing protein 11 isoform b
NM_001271348.2 NP_001258277.1 F-box/WD repeat-containing protein 11 isoform c
NM_001271349.2 NP_001258278.1 F-box/WD repeat-containing protein 11 isoform d
NM_001363353.2 NP_001350282.1 F-box/WD repeat-containing protein 11 isoform e
NM_001363354.2 NP_001350283.1 F-box/WD repeat-containing protein 11 isoform f
NM_001363355.2 NP_001350284.1 F-box/WD repeat-containing protein 11 isoform g
NM_134015.4 NP_598776.1 F-box/WD repeat-containing protein 11 isoform a
NM_001271347.2 NP_001258276.1 F-box/WD repeat-containing protein 11 isoform b
NM_001271348.2 NP_001258277.1 F-box/WD repeat-containing protein 11 isoform c
NM_001271349.2 NP_001258278.1 F-box/WD repeat-containing protein 11 isoform d
NM_001363353.2 NP_001350282.1 F-box/WD repeat-containing protein 11 isoform e
NM_001363354.2 NP_001350283.1 F-box/WD repeat-containing protein 11 isoform f
NM_001363355.2 NP_001350284.1 F-box/WD repeat-containing protein 11 isoform g
NM_134015.4 NP_598776.1 F-box/WD repeat-containing protein 11 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11896578 MGI
contributes to ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
11896578 MGI
enables ubiquitin-protein transferase activity IDA
IDA: 通过直接分析推断
11896578 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
11896578 MGI
involved in negative regulation of non-canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
11896578 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
18782782 MGI
involved in positive regulation of circadian rhythm IMP
IMP: 通过突变表型推断
18782782 MGI
involved in protein dephosphorylation IDA
IDA: 通过直接分析推断
18782782 MGI
involved in protein polyubiquitination IDA
IDA: 通过直接分析推断
11896578 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SCF ubiquitin ligase complex IDA
IDA: 通过直接分析推断
11896578 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
11896578 MGI
located in cytosol IDA
IDA: 通过直接分析推断
18782782 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18782782 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

F-box/WD repeat-containing protein 11

F-box and WD repeats protein beta-TrCP2

F-box and WD-40 domain protein 1B

F-box/WD repeat-containing protein 1B

homologous to Slimb protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04816 FBXW11 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21128 Fbxw11 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27646 Fbxw11 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fbxw11 NCBI NCBI:23291
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