ST3GAL6 - ST3 beta-galactoside alpha-2,3-sialyltransferase 6 Gene

中文名称：ST3 β-半乳糖苷 α-2,3-唾液酸转移酶 6

种属: Homo sapiens

同用名: SIAT10; ST3GALVI

关于 ST3GAL6

功能概要

该基因编码的蛋白质是唾液酸转移酶家族的成员。该家族的成员是将唾液酸从活化的胞苷 5'-单磷酸-N-乙酰神经氨酸转移到唾液酸化糖脂 (神经节苷脂) 末端位置或糖蛋白的 N-或 O-连接糖链的酶。这种蛋白质对作为糖脂底物的新乳四糖神经酰胺和新乳六糖神经酰胺具有高度特异性，并且可能有助于形成选择素配体和唾液酸 Lewis X，一种对细胞间识别和血型抗原很重要的碳水化合物。[RefSeq 提供，2016 年 4 月]

The protein encoded by this gene is a member of the Sialyltransferase family. Members of this family are Enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of Selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. [provided by RefSeq, Apr 2016]