2. Gene
  3. Bap1 - Brca1 associated protein 1 Gene

Bap1 - Brca1 associated protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: uch-x4; mKIAA0272; 2300006C11Rik

基因 ID: 104416 | 基因类型: protein coding

关于 Bap1

功能概要

Predicted to enable chromatin binding activity and thiol-dependent Deubiquitinase. Acts upstream of or within several processes, including macrophage homeostasis; regulation of cytokine production involved in inflammatory response; and regulation of inflammatory response. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of PR-DUB complex. Predicted to be active in cytoplasm. Is expressed in gonad; liver; and mammary gland. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in basal cell carcinoma and extrahepatic bile duct adenocarcinoma. Orthologous to human BAP1 (BRCA1 associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Bap1 基因产物(1)

mRNA Protein Name
NM_027088.2 NP_081364.1 ubiquitin carboxyl-terminal hydrolase BAP1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin DNA binding IDA
IDA: 通过直接分析推断
22878500 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9528852 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell population proliferation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in common myeloid progenitor cell proliferation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in erythrocyte differentiation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in erythrocyte maturation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in gene expression IMP
IMP: 通过突变表型推断
22878500 MGI
involved in granulocyte differentiation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in hematopoietic stem cell homeostasis IMP
IMP: 通过突变表型推断
22878500 MGI
involved in in utero embryonic development IMP
IMP: 通过突变表型推断
22878500 MGI
involved in leukocyte proliferation IMP
IMP: 通过突变表型推断
22878500 MGI
acts upstream of or within macrophage homeostasis IMP
IMP: 通过突变表型推断
26119930 MGI
involved in mitotic cell cycle IMP
IMP: 通过突变表型推断
22878500 MGI
involved in myeloid cell apoptotic process IMP
IMP: 通过突变表型推断
22878500 MGI
involved in neuron cellular homeostasis IMP
IMP: 通过突变表型推断
22878500 MGI
involved in neutrophil differentiation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in nucleate erythrocyte differentiation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in platelet morphogenesis IMP
IMP: 通过突变表型推断
22878500 MGI
acts upstream of or within regulation of cytokine production involved in inflammatory response IMP
IMP: 通过突变表型推断
26119930 MGI
acts upstream of or within regulation of inflammatory response IMP
IMP: 通过突变表型推断
26119930 MGI
involved in thrombocyte differentiation IMP
IMP: 通过突变表型推断
22878500 MGI
involved in tissue homeostasis IMP
IMP: 通过突变表型推断
22878500 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ubiquitin carboxyl-terminal hydrolase BAP1

BRCA1-associated protein 1

ubiquitin C-terminal hydrolase X4

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W327122 BAP1-IN-1 Inhibitor 99.86% 否
HY-158774 TG2-179-1 Inducer ≥99.0% 否
HY-169213 LN-439A Inhibitor / 否
HY-RS01364 BAP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07981 MAGI1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS12074 RNF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16963 Bap1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20444 Magi1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23406 Bap1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26953 Magi1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bap1 NCBI NCBI:8314
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