1. Gene
  2. Fancm - Fanconi anemia, complementation group M Gene

Fancm - Fanconi anemia, complementation group M Gene

种属: Mus musculus

同用名: D12Ertd364e; C730036B14Rik

基因 ID: 104806 | 基因类型: protein coding

关于 Fancm

功能概要

Predicted to enable DNA helicase activity; chromatin binding activity; and four-way junction DNA binding activity. Predicted to be involved in DNA metabolic process and positive regulation of protein monoubiquitination. Predicted to act upstream of or within cellular response to DNA damage stimulus. Predicted to be located in nucleoplasm. Predicted to be part of FANCM-MHF complex and Fanconi anaemia nuclear complex. Is expressed in lung; mandible; and temporal bone petrous part. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 15 and spermatogenic failure 28. Orthologous to human FANCM (FA complementation group M). [provided by Alliance of Genome Resources, Apr 2022]

Fancm 基因产物(2)

mRNA Protein Name
NM_001364447.1 NP_001351376.1 Fanconi anemia group M protein homolog isoform 2
NM_178912.4 NP_849243.2 Fanconi anemia group M protein homolog isoform 1
蛋白主名 其他名称

Fanconi anemia group M protein homolog

ATP-dependent RNA helicase FANCM

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fancm NCBI NCBI:57697