2. Gene
  3. Fermt3 - fermitin family member 3 Gene

Fermt3 - fermitin family member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Kindlin3

基因 ID: 108101 | 基因类型: protein coding

关于 Fermt3

功能概要

Enables Integrin binding activity. Involved in several processes, including Integrin activation; platelet aggregation; and regulation of cell-cell adhesion mediated by Integrin. Located in podosome. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; liver; and lung. Used to study leukocyte adhesion deficiency 3. Human ortholog(s) of this gene implicated in leukocyte adhesion deficiency 1 and leukocyte adhesion deficiency 3. Orthologous to human FERMT3 (FERM domain containing kindlin 3). [provided by Alliance of Genome Resources, Apr 2022]

Fermt3 基因产物(2)

mRNA Protein Name
NM_001362399.1 NP_001349328.1 fermitin family homolog 3
NM_153795.2 NP_722490.1 fermitin family homolog 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IDA
IDA: 通过直接分析推断
18278053 MGI
enables integrin binding IPI
IPI: 通过物理相互作用推断
19234461 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18278053 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in integrin activation IMP
IMP: 通过突变表型推断
18278053 MGI
involved in leukocyte cell-cell adhesion IMP
IMP: 通过突变表型推断
19234461 MGI
involved in platelet aggregation IMP
IMP: 通过突变表型推断
18278053 MGI
involved in regulation of cell-cell adhesion mediated by integrin IMP
IMP: 通过突变表型推断
19234461 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in podosome IDA
IDA: 通过直接分析推断
16876785 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fermitin family homolog 3

unc-112-related protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04866 FERMT3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21130 Fermt3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27648 Fermt3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fermt3 NCBI NCBI:83706
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