2. Gene
  3. Hspa1b - heat shock protein family A (Hsp70) member 1B Gene

Hspa1b - heat shock protein family A (Hsp70) member 1B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: HSP70; Hsp72; Hspa2; HSP70-1; HSP70.1; HSP70.2; Hsp70-2

基因 ID: 108348108 | 基因类型: protein coding

关于 Hspa1b

功能概要

Enables NF-kappaB binding activity and protease binding activity. Involved in several processes, including negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of vasoconstriction; and positive regulation of T cell mediated cytotoxicity. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and membrane raft. Part of protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; obesity; toxic shock syndrome; type 2 diabetes mellitus; and urinary tract Infection. Orthologous to human HSPA1B (heat shock protein family A (HSP70) member 1B). [provided by Alliance of Genome Resources, Apr 2022]

Hspa1b 基因产物(1)

mRNA Protein Name
NM_001329896.1 NP_001316825.1 heat shock 70 kDa protein 1B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9553041 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
16394269 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
23000394 RGD
involved in positive regulation of neuron differentiation IMP
IMP: 通过突变表型推断
23000394 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
23047067 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
22526757 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
20809232 RGD
involved in response to unfolded protein IMP
IMP: 通过突变表型推断
12397389 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane raft IDA
IDA: 通过直接分析推断
14499952 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heat shock 70 kDa protein 1B

Heat shock 70 kDa protein 2

heat shock 70 kDa protein 1

heat shock 70 kDa protein 1A/1B

heat shock 70kD protein 1B

heat shock protein 1B

heat shock protein 70

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06425 HSPA1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19261 Hspa1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25750 Hspa1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hspa1b NCBI NCBI:3304
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