2. Gene
  3. Irak2 - interleukin-1 receptor-associated kinase 2 Gene

Irak2 - interleukin-1 receptor-associated kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IRAK-2; 6330415L08Rik

基因 ID: 108960 | 基因类型: protein coding

关于 Irak2

功能概要

Predicted to enable protein heterodimerization activity; protein homodimerization activity; and protein serine/threonine kinase activity. Acts upstream of or within lipopolysaccharide-mediated signaling pathway; negative regulation of DNA-binding transcription factor activity; and positive regulation of NF-kappaB transcription factor activity. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Is expressed in several structures, including Peyer's patch; brain; genitourinary system; respiratory system; and thymus. Orthologous to human IRAK2 (interleukin 1 receptor associated kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Irak2 基因产物(2)

mRNA Protein Name
NM_001113553.1 NP_001107025.1 interleukin-1 receptor-associated kinase-like 2 isoform b
NM_172161.4 NP_751893.3 interleukin-1 receptor-associated kinase-like 2 isoform a
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11544529 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within lipopolysaccharide-mediated signaling pathway IDA
IDA: 通过直接分析推断
15082713 MGI
acts upstream of or within negative regulation of DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
15082713 MGI
acts upstream of or within positive regulation of NF-kappaB transcription factor activity IDA
IDA: 通过直接分析推断
15082713 MGI
NOT acts upstream of or within positive regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
12220507 MGI
NOT acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
12220507 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-1 receptor-associated kinase-like 2

interleukin-1 receptor-associated kinase 2c

mu-IRAK-2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06896 IRAK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19016 Irak2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25505 Irak2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Irak2 NCBI NCBI:3656
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