2. Gene
  3. Ampd2 - adenosine monophosphate deaminase 2 Gene

Ampd2 - adenosine monophosphate deaminase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ampd-2; m4521Dajl; 1200014F01Rik

基因 ID: 109674 | 基因类型: protein coding

关于 Ampd2

功能概要

Enables AMP deaminase activity. Involved in ATP metabolic process and purine ribonucleotide metabolic process. Acts upstream of or within several processes, including IMP biosynthetic process; Cholesterol homeostasis; and energy homeostasis. Predicted to be active in cytosol. Is expressed in several structures, including endocrine gland; genitourinary system; nervous system; and vascular system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 63 and pontocerebellar hypoplasia type 9. Orthologous to human AMPD2 (adenosine monophosphate deaminase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ampd2 基因产物(4)

mRNA Protein Name
NM_001289719.1 NP_001276648.1 AMP deaminase 2 isoform b
NM_001289720.1 NP_001276649.1 AMP deaminase 2 isoform a
NM_001346665.1 NP_001333594.1 AMP deaminase 2 isoform d
NM_028779.5 NP_083055.1 AMP deaminase 2 isoform b
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables AMP deaminase activity IMP
IMP: 通过突变表型推断
22212473 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in AMP metabolic process IMP
IMP: 通过突变表型推断
22212473 MGI
involved in ATP metabolic process IGI
IGI: 通过遗传相互作用推断
23911318 MGI
involved in ATP metabolic process IMP
IMP: 通过突变表型推断
22212473 MGI
involved in GTP metabolic process IGI
IGI: 通过遗传相互作用推断
23911318 MGI
involved in GTP metabolic process IMP
IMP: 通过突变表型推断
22212473 MGI
acts upstream of or within IMP biosynthetic process IMP
IMP: 通过突变表型推断
23911318 MGI
involved in IMP salvage IMP
IMP: 通过突变表型推断
22212473 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
18974039 MGI
acts upstream of or within energy homeostasis IMP
IMP: 通过突变表型推断
23911318 MGI
acts upstream of or within nucleotide metabolic process IMP
IMP: 通过突变表型推断
22212473 MGI
acts upstream of or within podocyte development IMP
IMP: 通过突变表型推断
25361754 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

AMP deaminase 2

adenosine monophosphate deaminase 2 (isoform L)

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103673 AMPD2 inhibitor 1 Inhibitor 99.52% 否
HY-152199 AMPD2 inhibitor 2 Inhibitor / 否
HY-RS00667 AMPD2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18984 Ampd2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25473 Ampd2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ampd2 NCBI NCBI:271
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