2. Gene
  3. LILRA1 - leukocyte immunoglobulin like receptor A1 Gene

LILRA1 - leukocyte immunoglobulin like receptor A1 Gene

  • 基因
  • 蛋白
  • 相关产品

中文名称：白细胞免疫球蛋白样受体 A1

种属: Homo sapiens

同用名: LIR6; CD85I; LIR-6

基因 ID: 11024 | 基因类型: protein coding

关于 LILRA1

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,593,632-54,602,381 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 303 orthologues and 25 paralogues. Biased expression in appendix (RPKM 8.6), spleen (RPKM 6.8) and 6 other tissues.

功能概要

该基因编码白细胞免疫球蛋白样受体 (LIR) 家族的激活成员，该家族位于染色体区域 19q13.4 的基因簇中。编码的蛋白质主要在 B 细胞中表达，与主要组织相容性复合体 I 类配体相互作用，并有助于调节免疫反应。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2013 年 5 月]

This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

LILRA1 基因产物(3)

mRNA Protein Name
NM_001278318.2 NP_001265247.1 leukocyte immunoglobulin-like receptor subfamily A member 1 isoform 2 precursor
NM_001278319.1 NP_001265248.1 leukocyte immunoglobulin-like receptor subfamily A member 1 isoform 3 precursor
NM_006863.4 NP_006854.1 leukocyte immunoglobulin-like receptor subfamily A member 1 isoform 1 precursor

LILRA1 蛋白结构

Ig_2

Ig_2: Immunoglobulin domain (28 - 118)

Ig_3

Ig_3: Immunoglobulin domain (124 - 199)

Ig_2

Ig_2: Immunoglobulin domain (225 - 317)

Ig_3

Ig_3: Immunoglobulin domain (325 - 400)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 489 a.a.
蛋白主名 其他名称

leukocyte immunoglobulin-like receptor subfamily A member 1

CD85 antigen-like family member I

重组 LILRA1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77440 LILRA1/LIR-6/CD85i Protein, Human (HEK293, His) O75019-1 (P17-N461) ≥95%
HY-P78169 LILRA1/LIR-6/CD85i Protein, Human (Biotinylated, HEK293, His-Avi) O75019 (P17-N461) ≥95%
HY-P78479 LILRA1/LIR-6/CD85i Protein, Human (HEK293, His-Avi) O75019 (P17-N461) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07645 LILRA1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
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