TREH - trehalase Gene

中文名称：海藻糖酶

种属: Homo sapiens

同用名: TRE; TREA; TREHD

基因 ID: 11181 | 基因类型: protein coding

关于 TREH

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:118,657,316-118,679,650 (from NCBI)

This gene has 5 transcripts (splice variants), 178 orthologues and is associated with 2 phenotypes. Biased expression in duodenum (RPKM 44.4), small intestine (RPKM 43.7) and 1 other tissue.

功能概要

该基因编码一种水解海藻糖的酶，海藻糖是一种由两个葡萄糖分子形成的二糖，主要存在于真菌、植物和昆虫中。该基因的部分重复位于 11 号染色体上的该基因座附近。已发现该基因的两种编码不同亚型的转录物变体。[RefSeq 提供，2014 年 7 月]

This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, Plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

TREH 基因产物(2)

mRNA	Protein	Name
NM_001301065.2	NP_001287994.1	trehalase isoform 2 precursor
NM_007180.3	NP_009111.2	trehalase isoform 1 precursor

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables alpha,alpha-trehalase activity	IDA IDA: 通过直接分析推断	8773341	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in trehalose catabolic process	IDA IDA: 通过直接分析推断	9427547	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TREH 蛋白结构

Trehalase

0
100
200
300
400
500
582 a.a.

蛋白主名

其他名称

trehalase

alpha,alpha-trehalose glucohydrolase

关联疾病

疾病名称

别名

Trehalase Deficiency

Trehalose Intolerance	Isolated Trehalose Intolerance
TREHD	Alpha, Alpha-Trehalase Deficiency

Lactase Deficiency, Congenital

Congenital Lactase Deficiency	Disaccharide Intolerance Ii
Congenital Alactasia	Congenital Alactasia Syndrome
Congenital Lactose Intolerance	Congenital Lactose Malabsorption
Hereditary Alactasia	Alactasia, Congenital
Cld	COLACD
Disaccharide Intolerance Type 2	Cld - [Congenital Lactase Deficiency]
Disaccharide Intolerance 2	Lactose Intolerance Of Newborn
Hereditary Lactase Deficiency

Sucrase-Isomaltase Deficiency, Congenital

Congenital Sucrase-Isomaltase Deficiency	CSID
Si Deficiency	Congenital Sucrose Intolerance
Disaccharide Intolerance	Sucrase-Isomaltase Deficiency
Disaccharide Intolerance I	Congenital Sucrose-Isomaltose Malabsorption
Sucrose-Isomaltose Malabsorption, Congenital	Sucrose Intolerance, Congenital
Congenital Sucrase-Isomaltose Malabsorption	Congenital Sucrose-Isomaltase Malabsorption
Disaccharide Intolerance, 1	Sucrose Intolerance Congenital
Sucrose-Isomaltase Malabsorption, Congenital	Disaccharidase Deficiency
Invertase Deficiency	Sucrase-Alpha-Dextrinase Deficiency
Disaccharide Intolerance Type I	Csid - [Congenital Sucrase-Isomaltase Deficiency]
Sucrose Intolerance Of Newborn	Sucrose Intolerance
Sucrase Deficiency	Disaccharide Malabsorption
Intestinal Disaccharidase Deficiency

Oligohydramnios

Oligohydramnios - Delivered	Antepartum Oligohydramnios
Delivered Oligohydramnios	Oligohydramnios, Antepartum Condition Or Complication
Deficient Liquor	Oligohydramnios, Unspecified Trimester
Reduced Liquor Volume

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis	ALS
Lou Gehrig Disease	Amyotrophic Lateral Sclerosis Type 1
Charcot Disease	ALS1
Amyotrophic Lateral Sclerosis, Susceptibility To	Fals
Lou Gehrig'S Disease	Mnd
Motor Neuron Disease	Familial Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial	Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Bulbar	Motor Neurone Disease
Amyotrophic Lateral Sclerosis With Dementia	Dementia With Amyotrophic Lateral Sclerosis
Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Sclerosis, Lateral, Amyotrophic
Sclerosis, Lateral, Amyotrophic, Type 1	Amyotrophic Sclerosis
Als - [Amyotrophic Lateral Sclerosis]	Wasting Palsy
Amyotrophic Paralysis	Amyotrophy Lateral Sclerosis
Wasting Paralysis	Spinal Progressive Amyotrophy
Progressive Atrophic Paralysis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS15001	TREH Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	TREH	VGNC	VGNC:36297
Canis familiaris	TREH	VGNC	VGNC:47792
Rattus norvegicus	TREH	RGD	RGD:61831
Macaca mulatta	TREH	VGNC	VGNC:101418
Mus musculus	TREH	MGD	MGI:1926230
Others	TREH	NCBI

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TREH - trehalase Gene

关于 TREH

功能概要

TREH 基因产物(2)

TREH 蛋白结构

关联疾病

直系同源

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TREH - trehalase Gene

关于 TREH

功能概要

TREH 基因产物(2)

TREH 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z