2. Gene
  3. Egln3 - egl-9 family hypoxia-inducible factor 3 Gene

Egln3 - egl-9 family hypoxia-inducible factor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Phd3; SM-20; Hif-p4h-3; 2610021G09Rik

基因 ID: 112407 | 基因类型: protein coding

关于 Egln3

功能概要

Enables peptidyl-proline dioxygenase activity. Involved in regulation of cell population proliferation and regulation of neuron apoptotic process. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including gallbladder; genitourinary system; gut; skeletal musculature; and somite. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human EGLN3 (egl-9 family hypoxia inducible factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Egln3 基因产物(1)

mRNA Protein Name
NM_028133.2 NP_082409.2 prolyl hydroxylase EGLN3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidyl-proline dioxygenase activity IDA
IDA: 通过直接分析推断
24030251 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
18332118 MGI
involved in regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
18332118 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prolyl hydroxylase EGLN3

HIF-PH3

HIF-prolyl hydroxylase 3

HPH-3

hypoxia-inducible factor prolyl hydroxylase 3

prolyl hydroxylase domain-containing protein 3

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-168533 ZG-2305 Inhibitor / 否
HY-RS04214 EGLN3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20396 Egln3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26905 Egln3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Egln3 NCBI NCBI:112399
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