1. Gene
  2. SHLD3 - shieldin complex subunit 3 Gene

SHLD3 - shieldin complex subunit 3 Gene

中文名称:shieldin 复合亚基 3

种属: Homo sapiens

同用名: RINN1; CTC-534A2.2

基因 ID: 112441434 | 基因类型: protein coding

关于 SHLD3

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,625,027-65,630,928 (from NCBI)

This gene has 2 transcripts (splice variants) and 92 orthologues.

功能概要

通过同源重组参与双链断裂修复的负调控;通过非同源末端连接对双链断裂修复进行正调控;和同种型转换的正向调节。位于双链断裂位点。 [由基因组资源联盟提供,2022 年 4 月]

Involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Located in site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022]

SHLD3 基因产物(1)

mRNA Protein Name
NM_001365341.2 NP_001352270.1 shieldin complex subunit 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
29656893 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome IDA
IDA: 通过直接分析推断
29656893 GOA
located in site of double-strand break IDA
IDA: 通过直接分析推断
29656893 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

shieldin complex subunit 3

REV7-interacting novel NHEJ regulator 1

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SHLD3 RGD RGD:41350418
Mus musculus SHLD3 MGD MGI:6194609