1. Gene
  2. GLMP - glycosylated lysosomal membrane protein Gene

GLMP - glycosylated lysosomal membrane protein Gene

中文名称:糖基化溶酶体膜蛋白

种属: Homo sapiens

同用名: NCU-G1; C1orf85

基因 ID: 112770 | 基因类型: protein coding

关于 GLMP

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,292,688-156,295,679 (from NCBI)

This gene has 16 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in prostate (RPKM 30.2), placenta (RPKM 24.2) and 25 other tissues.

功能概要

参与 RNA 聚合酶 II 对转录的正调控。位于胞质溶胶中;溶酶体;和核。 [由基因组资源联盟提供,2022 年 4 月]

Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; lysosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

GLMP 基因产物(5)

mRNA Protein Name
NM_001256604.2 NP_001243533.1 glycosylated lysosomal membrane protein isoform 2 precursor
NM_001256605.2 NP_001243534.1 glycosylated lysosomal membrane protein isoform 3
NM_001256608.2 NP_001243537.1 glycosylated lysosomal membrane protein isoform 4 precursor
NM_001256609.2 NP_001243538.1 glycosylated lysosomal membrane protein isoform 5
NM_144580.3 NP_653181.1 glycosylated lysosomal membrane protein isoform 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18021396 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
18021396 GOA
located in lysosome IDA
IDA: 通过直接分析推断
19556463 GOA
located in nucleus IDA
IDA: 通过直接分析推断
18021396 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GLMP 蛋白结构

NCU-G1

NCU-G1: Lysosomal transcription factor, NCU-G1 (55 - 400)

  • 0
  • 100
  • 200
  • 300
  • 406 a.a.
蛋白主名 其他名称

glycosylated lysosomal membrane protein

kidney lysosomal membrane protein

关联疾病

疾病名称 别名
Multilocular Clear Cell Renal Cell Carcinoma

Cystadenocarcinoma Of Kidney

Renal Cystadenocarcinoma

Progressive Myoclonus Epilepsy 4

Action Myoclonus-Renal Failure Syndrome

Amrf

Epm4

Myoclonus-Nephropathy Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus GLMP MGD MGI:1913318
Felis catus GLMP VGNC VGNC:62583
Macaca mulatta GLMP VGNC VGNC:73030
Canis familiaris GLMP VGNC VGNC:41265
Bos taurus GLMP VGNC VGNC:29409
Rattus norvegicus GLMP RGD RGD:1303130