1. Gene
  2. Abcg1 - ATP binding cassette subfamily G member 1 Gene

Abcg1 - ATP binding cassette subfamily G member 1 Gene

种属: Mus musculus

同用名: Abc8; White

基因 ID: 11307 | 基因类型: protein coding

关于 Abcg1

功能概要

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The human protein is involved in macrophage Cholesterol efflux and may regulate cellular lipid homeostasis in Other cell types. [provided by RefSeq, Jul 2008]

Abcg1 基因产物(1)

mRNA Protein Name
NM_009593.2 NP_033723.1 ATP-binding cassette sub-family G member 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to high density lipoprotein particle stimulus IDA
IDA: 通过直接分析推断
15210959 MGI
involved in cholesterol efflux IMP
IMP: 通过突变表型推断
16556852 MGI
acts upstream of or within cholesterol transport IDA
IDA: 通过直接分析推断
15319426 MGI
involved in high-density lipoprotein particle remodeling IMP
IMP: 通过突变表型推断
16556852 MGI
involved in low-density lipoprotein particle remodeling IMP
IMP: 通过突变表型推断
16556852 MGI
involved in negative regulation of lipid storage IMP
IMP: 通过突变表型推断
16556852 MGI
involved in positive regulation of cholesterol biosynthetic process IMP
IMP: 通过突变表型推断
17916878 MGI
involved in positive regulation of cholesterol efflux IDA
IDA: 通过直接分析推断
15210959 MGI
involved in regulation of cholesterol metabolic process IMP
IMP: 通过突变表型推断
16556852 MGI
involved in reverse cholesterol transport IMP
IMP: 通过突变表型推断
17657311 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
17916878 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
16556852 MGI
located in recycling endosome IDA
IDA: 通过直接分析推断
16556852 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ATP-binding cassette sub-family G member 1

ATP-binding cassette 8

ATP-binding cassette transporter 8

ATP-binding cassette, sub-family G (WHITE), member 1

white protein homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abcg1 NCBI NCBI:9619