GOLM2 - golgi membrane protein 2 Gene

中文名称：高尔基体膜蛋白 2

种属: Homo sapiens

同用名: H63; CASC4

关于 GOLM2

功能概要

该基因表达水平的增加与 HER-2/neu 原癌基因的过度表达有关。在大约 30% 的人类乳腺癌和 20% 的人类卵巢癌中发现了这种原癌基因的扩增和由此产生的过度表达。已经为该基因鉴定了编码不同亚型的可变剪接变体。[RefSeq 提供，2010 年 12 月]

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]