2. Gene
  3. Npnt - nephronectin Gene

Npnt - nephronectin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nctn; POEM; 1110009H02Rik

基因 ID: 114249 | 基因类型: protein coding

关于 Npnt

功能概要

Enables Integrin binding activity. Involved in several processes, including cell-cell adhesion mediated by integrin; pilomotor reflex; and positive regulation of Alkaline Phosphatase activity. Acts upstream of or within several processes, including branching involved in ureteric bud morphogenesis; positive regulation of cell-substrate adhesion; and positive regulation of transforming growth factor beta receptor signaling pathway. Located in basement membrane; extracellular region; and smooth muscle contractile fiber. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human NPNT (nephronectin). [provided by Alliance of Genome Resources, Apr 2022]

Npnt 基因产物(5)

mRNA Protein Name
NM_001029836.2 NP_001025007.1 nephronectin isoform b precursor
NM_001287101.1 NP_001274030.1 nephronectin isoform c precursor
NM_001287102.1 NP_001274031.1 nephronectin isoform d precursor
NM_001287103.1 NP_001274032.1 nephronectin isoform e
NM_033525.3 NP_277060.2 nephronectin isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IDA
IDA: 通过直接分析推断
19342381 MGI
enables integrin binding IPI
IPI: 通过物理相互作用推断
11546798 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within branching involved in ureteric bud morphogenesis IMP
IMP: 通过突变表型推断
17537792 MGI
involved in cell-cell adhesion mediated by integrin IDA
IDA: 通过直接分析推断
19342381 MGI
acts upstream of or within cell-matrix adhesion IDA
IDA: 通过直接分析推断
11470831 MGI
acts upstream of or within cell-matrix adhesion IPI
IPI: 通过物理相互作用推断
11470831 MGI
involved in cellular response to tumor necrosis factor IDA
IDA: 通过直接分析推断
21689636 MGI
involved in establishment of protein localization IMP
IMP: 通过突变表型推断
21335239 MGI
acts upstream of or within extracellular matrix organization IDA
IDA: 通过直接分析推断
18757743 MGI
involved in pilomotor reflex IMP
IMP: 通过突变表型推断
21335239 MGI
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
19944102 MGI
involved in positive regulation of alkaline phosphatase activity IDA
IDA: 通过直接分析推断
19944102 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: 通过直接分析推断
18757743 MGI
involved in positive regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
19944102 MGI
involved in positive regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
21335239 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
21335239 MGI
acts upstream of or within positive regulation of transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
17537792 MGI
involved in smooth muscle cell differentiation IDA
IDA: 通过直接分析推断
21335239 MGI
acts upstream of transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
17537792 MGI
acts upstream of or within ureteric bud development IMP
IMP: 通过突变表型推断
17537792 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
18757743 MGI
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
21335239 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
11470831 MGI
located in extracellular matrix IPI
IPI: 通过物理相互作用推断
11470831 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
19944102 MGI
located in smooth muscle contractile fiber IDA
IDA: 通过直接分析推断
21335239 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nephronectin

preosteoblast EGF-like repeat protein with MAM domain

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09493 NPNT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20785 Npnt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27299 Npnt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npnt NCBI NCBI:255743
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