2. Gene
  3. Itga6 - integrin subunit alpha 6 Gene

Itga6 - integrin subunit alpha 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 114517 | 基因类型: protein coding

关于 Itga6

功能概要

Enables laminin binding activity. Involved in cell-cell adhesion; cellular response to organic cyclic compound; and positive regulation of cell-substrate adhesion. Located in adherens junction and filopodium. Part of Integrin alpha6-beta4 complex. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGA6 (Integrin subunit alpha 6). [provided by Alliance of Genome Resources, Apr 2022]

Itga6 基因产物(1)

mRNA Protein Name
NM_053725.2 NP_446177.2 integrin alpha-6 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables laminin binding IPI
IPI: 通过物理相互作用推断
16608848 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
13130099 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
16557522 RGD
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
13130099 RGD
involved in positive regulation of cell-substrate adhesion IMP
IMP: 通过突变表型推断
13130099 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in adherens junction IDA
IDA: 通过直接分析推断
16608848 RGD
located in filopodium IDA
IDA: 通过直接分析推断
13130099 RGD
part of integrin alpha6-beta4 complex IDA
IDA: 通过直接分析推断
13130099 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integrin alpha-6

integrin, alpha 6

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06953 ITGA6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18523 Itga6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25005 Itga6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itga6 NCBI NCBI:3655
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