2. Gene
  3. Nppc - natriuretic peptide C Gene

Nppc - natriuretic peptide C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 114593 | 基因类型: protein coding

关于 Nppc

功能概要

Enables hormone activity. Involved in several processes, including negative regulation of biosynthetic process; positive regulation of cGMP-mediated signaling; and positive regulation of osteoblast differentiation. Acts upstream of or within receptor guanylyl cyclase signaling pathway. Located in extracellular space and secretory granule. Biomarker of aortic valve stenosis and heart disease. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPPC (natriuretic peptide C). [provided by Alliance of Genome Resources, Apr 2022]

Nppc 基因产物(1)

mRNA Protein Name
NM_053750.1 NP_446202.1 C-type natriuretic peptide precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hormone activity IDA
IDA: 通过直接分析推断
12746286 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cGMP-mediated signaling IDA
IDA: 通过直接分析推断
14691198 RGD
involved in negative regulation of DNA biosynthetic process IDA
IDA: 通过直接分析推断
12746286 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
17562543 RGD
involved in negative regulation of collagen biosynthetic process IDA
IDA: 通过直接分析推断
12746286 RGD
involved in positive regulation of cGMP-mediated signaling IDA
IDA: 通过直接分析推断
12746286 RGD
involved in positive regulation of mast cell degranulation IDA
IDA: 通过直接分析推断
9663691 RGD
involved in positive regulation of osteoblast differentiation IDA
IDA: 通过直接分析推断
17562543 RGD
involved in positive regulation of uterine smooth muscle relaxation IDA
IDA: 通过直接分析推断
9663691 RGD
acts upstream of or within receptor guanylyl cyclase signaling pathway IDA
IDA: 通过直接分析推断
17951249 RGD
involved in regulation of smooth muscle cell proliferation IEP
IEP: 通过表达模式推断
11742834 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
9042593 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
16677483 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11476746 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
16677483 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
19666697 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-type natriuretic peptide

natriuretic peptide precursor C

natriuretic peptide precursor type C

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09496 NPPC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20311 Nppc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26819 Nppc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nppc NCBI NCBI:4880
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