2. Gene
  3. Actb - actin, beta Gene

Actb - actin, beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Actx; beta-actin; E430023M04Rik

基因 ID: 11461 | 基因类型: protein coding

关于 Actb

功能概要

This gene encodes a member of the actin family of proteins. Actins are highly conserved proteins that are among the most abundant proteins in eukaryotic cells and are involved in cell motility, structure, and integrity. Localization, stability, and translation of the transcribed mRNA are regulated through the binding of multiple factors to its 3' UTR sequence. Homozygous knockout mice for this gene exhibit embryonic lethality. Numerous pseudogenes of this gene have been identified in the mouse genome. [provided by RefSeq, Sep 2015]

Actb 基因产物(1)

mRNA Protein Name
NM_007393.5 NP_031419.1 actin, cytoplasmic 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10683146 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of protein binding IDA
IDA: 通过直接分析推断
19118186 MGI
involved in regulation of synaptic vesicle endocytosis IDA
IDA: 通过直接分析推断
27840001 MGI
involved in regulation of synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
27840001 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
27840001 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
27840001 MGI
located in brush border IDA
IDA: 通过直接分析推断
33129760 MGI
is active in calyx of Held IDA
IDA: 通过直接分析推断
27840001 MGI
is active in calyx of Held IMP
IMP: 通过突变表型推断
27840001 MGI
located in cortical cytoskeleton IDA
IDA: 通过直接分析推断
18723693 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
24327345 MGI
located in cytoskeleton IDA
IDA: 通过直接分析推断
24327345 MGI
located in cytosol IDA
IDA: 通过直接分析推断
11931770 MGI
located in nucleus IDA
IDA: 通过直接分析推断
29042633 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

actin, cytoplasmic 1

A-X actin-like protein

actin, beta, cytoplasmic

melanoma X-actin

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16025 EOC317 Inhibitor 98.05% 否
HY-RS00215 ACTB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10891 POTEF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17630 Actb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24090 Actb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Actb NCBI NCBI:60
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