2. Gene
  3. Abcg5 - ATP binding cassette subfamily G member 5 Gene

Abcg5 - ATP binding cassette subfamily G member 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 114628 | 基因类型: protein coding

关于 Abcg5

功能概要

Predicted to enable ATPase-coupled transmembrane transporter activity and protein heterodimerization activity. Predicted to contribute to ATP binding activity; ATP hydrolysis activity; and Cholesterol transfer activity. Involved in several processes, including bile acid signaling pathway; lipid homeostasis; and response to muscle activity. Predicted to be located in apical plasma membrane. Predicted to be integral component of plasma membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex and receptor complex. Used to study sitosterolemia. Biomarker of cholestasis; non-alcoholic fatty liver disease; and obesity. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5). [provided by Alliance of Genome Resources, Apr 2022]

Abcg5 基因产物(1)

mRNA Protein Name
NM_053754.2 NP_446206.2 ATP-binding cassette sub-family G member 5
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cholesterol homeostasis IEP
IEP: 通过表达模式推断
23117815 RGD
involved in response to ionizing radiation IEP
IEP: 通过表达模式推断
17132608 RGD
involved in response to muscle activity IEP
IEP: 通过表达模式推断
23117815 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
15710224 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
23117815 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17109865 RGD
involved in triglyceride homeostasis IEP
IEP: 通过表达模式推断
23117815 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATP-binding cassette sub-family G member 5

ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1)

ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)

ATP-binding cassette, subfamily G (WHITE), member 5

sterolin 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0288 Lycorine 99.87% 否
HY-RS00081 ABCG5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-N9516 Taurodehydrocholic acid / 否
HY-RS17755 Abcg5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24222 Abcg5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abcg5 NCBI NCBI:64240
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